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CONFERENCIAS MAGISTRALES

Vol. 30. Supl. 1, Abril-Junio 2007 pp S82-S87

C CO

LEG

IOM

EXICANO DE ANESTESIOLOG

ÍA

A.C

.

AN TES

SO

CIEDAD

MEXICANA DE ANEST

ESIO LOG

ÍA

Anestesiología

Anestesiología

Revista

Mexicana de

Anestesiología

Anestesiología

Anesthesia for the Child with Congenital Heart

Disease (CHD) for Non-cardiac Surgery

William J. Greeley, MD

The Children’s Hospital of Philadelphia. Department of Anesthesia. University of Pennsylvania School of Medicine

Stage I Procedure

Stage II Procedure

Superior Cavopulmonary Connection with Takedown of B-T Shunt Removes Volume Load on Single Ventricle

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SUSTRAÍDODE-M.E.D.I.G.R.A.P.H.I.C

:ROP ODAROBALE FDP

VC ED AS, CIDEMIHPARG

ARAP

ACIDÉMOIB ARUTARETIL :CIHPARGIDEM

OBJECTIVES

• Demographics

• Determinants of physiologic function • Surgical procedures

• Anesthetic management

DEMOGRAPHICS OF CHD IN USA

• 21,000-43,000 live births annually • 20,000 cardiac surgical procedures • Over 80% survival to third decade • Prevalence 500,000-800,000 • Heterogeneous population Stage III

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PREVALENCE OF CONGENITAL HEART

MALFORMATIONS

Lesion Infants Children Adults

(%) (%) (%)

Ventricular septal defect 28.3 24 15

Patent ductus arteriosus 12.5 15 15.5

Atrial septal defect 9.7 12 16

Coarctation 8.8 4.5 8

Transposition of great art 8 4.5 2

Hyoplastic left heart synd 7.8 — —

Tetralogy of Fallot 7 11 15.5

Pulmonary stenosis 6 11 15

Aortic stenosis 3.5 6.5 5

Truncus arteriosus 2.7 0.5 —

Tricuspid atresia 1 1.5 1

AORTIC STENOSIS AFTER 25 YEARS

FONTAN NYHA CLASS

Fontan F, et al: Circulation 81:1520, 1990

OBJECTIVES

• Demographics

• Determinants of physiologic function • Surgical procedures

• Anesthetic management

DETERMINANTS OF PHYSIOLOGIC FUNCTION

• Sequelae • Complications • Palliation • Correction

COMMON SEQUELAE

• Arrhythmia

• Ventricular dysfunction • Hemodynamic disturbance • Pulmonary vascular disease

DETERMINANTS OF PHYSIOLOGIC FUNCTION

• sequelae Hospital Admission Rate - Mayo Clinic

0

20

40

60

80

100

0

2

4

6

8

10 12 14

years followup

per

c

e

n

t

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edigraphic.com

SUSTRAÍDODE-M.E.D.I.G.R.A.P.H.I.C

:ROP ODAROBALE FDP

VC ED AS, CIDEMIHPARG

ARAP

ACIDÉMOIB ARUTARETIL :CIHPARGIDEM DETERMINANTS OF PHYSIOLOGIC FUNCTION

• sequelae • complications • palliation

• e.g. single ventricle & Fontan

DETERMINANTS OF PHYSIOLOGIC FUNCTION

• Sequelae • Complications • Palliation • Correction

FONTAN OPERATION

• Functional level -NYHA

• Arrhythmia 20 – 30%

• Ventricular function 10 – 20%

• Pulmonary vascular disease 25%

• Hemodynamic sequelae 100%

• Protein losing enteropathy 5 – 10%

• Thromboembolism 15 – 20%

OBJECTIVES

• Demographics

• Determinants of physiologic function • Surgical procedures

• Anesthetic management

SURGERY IN CHILDREN WITH CHD

• Dental Procedures • General surgery • Urology • Trauma

• Orthopedic surgery

CHOP NON-CARDIAC SURGERY 2004

• Requests 945/CVA 424

• PS II (154), PS III (195), PS IV (75) • Elective (400 ), emergency (24)

• Day Surgery (274), overnight stay (150)

• Simple procedures (60%) – BMT, T/A, circumcision, hernia • Complex procedures (40%) – TEF, brain tumor, tumor

resection, transplant, etc.

SURGERY IN ADULTS WITH CHD

• Labor and delivery • Trauma

• Orthopedic surgery • General surgery • Cardiac surgery

OBJECTIVES

• Demographics

• Determinants of physiologic function • Surgical procedures

• Anesthetic management

Table I. Personnel and Services Recommended or Required for Regional ACHD Centers

Type of Service or Personel Local Care Regional ACHD Center

Pediatric ACHD cardiologist Optional One or several 24/7*

Adult medical ACHD cardiologist Optional One or several 24/7*

Mid-level practitioner Optional Two/several

Congenital heart surgeon No Two/several 24/7*

Cardiac anesthesia No Several 24/7*

Echocardiography** Refer to regional ACHD center Two/several 24/7*

Includes TEE, intraoperative TEE (required for surgery)

Diagnostic catheterization** Refer to regional ACHD center Yes 24/7*

Noncoronary interventional Refer to regional ACHD center Yes 24/7*

catheterization**

Electrophysiology** Consult regional ACHD center Yes 24/7*

unless unrelated to CHD

Exercise testing Standard Echo, radionuclide, cardiopulmonary, metabo

Transplant Optional Heart, lung, heart-lung desirable

Cardiac imaging/radiology services Optional CT scan, cardiac MRI with fast-pulse sequen

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Cardiac pathology Optional Yes

Information technology Optional • Data collection

Other • Interface with regional • Database support

ACHD center • Interface with local practitioners,

• Data collection including internet-based applications

• Participation in patient-care • Quality assessment review and protocols and best- practice • Optional development of best practice guid

guidelines review • Adolescent transitional unit

• High risk obstetrics • Genetics

• Rehabilitation services • Social services • Vocational services • Financial counselors

* «24/7» denotes availability 24 hours/day, 7 days/week. **These modalities must be supervised/performed and interpre-ted by physicians with specific skills and knowledge.

DESIRABLE HEMODYNAMIC OBJECTIVES

Preload PVR SVR HR contractility

ASD (L→R) ↑ ↑ ↓ N N

PDA (L→R) ↑ ↑ ↓ N N

VSD (L→R) ↑ ↑ ↓ N N

VSD (R→L) N ↓ ↑ N N

AS ↑ N ↑* ↓* N-↑

IHSS ↑ N N-↑ ↓* ↓*

Valvar PS ↑ ↓ N ↓ ↑

Infundibular PS ↑ ↓ N ↓ ↓*

Coarctation ↑ N ↓ N N

MS ↑ N-↓ N ↓* N-↑

MR ↑ N-↓ ↓ N-↑ N-↑

AI ↑ N ↓ N-↑ N-↑

* overriding consideration

ANESTHETIC MANAGEMENT

• More important to be guided by a safe, familiar, estab-lished anesthetic technique than to have a detailed un-derstanding of the specific pathophysiologic lesion

• Patient evaluation

• Cardiologist communication

EVALUATION OF CARDIAC STATUS

• Activity tolerance • Growth pattern

• Congestive heart failure • Magnitude of cyanosis • Medications

• Cardiologist evaluation

FORMULATION OF AN ANESTHETIC PLAN

• Patient considerations • Operative considerations • Postoperative considerations

PATIENT CONSIDERATIONS

• Associated conditions –e.g Chr 22 • Airway –e.g. tracheal stenosis • Psychosocial issues –e.g. depression • Medications

• Hematocrit –e.g. cyanosis

OPERATIVE CONSIDERATIONS

• SBE prophylaxis –e.g. AHA

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SUSTRAÍDODE-M.E.D.I.G.R.A.P.H.I.C

:ROP ODAROBALE FDP

VC ED AS, CIDEMIHPARG

ARAP

ACIDÉMOIB ARUTARETIL :CIHPARGIDEM • VR & PBF, emboli & R->L shunts

• Single lung ventilation

• Cyanosis, PBF, AV malformations

POSTOPERATIVE CONSIDERATIONS

• PACU vs ICU • Patient comfort

• Pain – SVR & PVR changes, neuraxial analgesia • N & V – fluids

• Fluid management

CONCLUSIONS

• Physiologic spectrum wide

• Expected outcome of a specific lesion and sequelae • (Arrythmia, ventricular dysfunction, hemodynamic

residua, pulmonary vascular disease) • Formulation of anesthetic plan

• Response to provocative conditions • General

• Specific

Figure

Table I. Personnel and Services Recommended or Required for Regional ACHD Centers

Referencias

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