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Regulation of subcellular location and activity of Cdc2-cyclinb1 is involved in bendamustine-induced G2 arrest

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1043 ISSN 0326-2383

KEY WORDS: Bendamustine, Cdc2-CyclinB1 complex, G2 arrest, RPMI-8226.

* Authors to whom correspondence should be addressed. E-mail:hongzhu@zju.edu.cn (Hong Zhu), yang924@zju.edu.cn (Bo Yang).

Latin American Journal of Pharmacy

(formerly

Acta Farmacéutica Bonaerense)

Lat. Am. J. Pharm.

31

(7): 1043-51 (2012)

Regular Article Received: June 12, 2012 Revised version: September 4, 2012 Accepted: September 5, 2012

Regulation of Subcellular Location and Activity of Cdc2-CyclinB1

is Involved in Bendamustine-induced G2 Arrest

Guan-Yu LIN

1

, Ling-Juan HE

1

, Yan YAN

1

, Duo-Duo WANG

1

,

Kai-Zan ZHUANG

2

, Hong ZHU

1

* & Bo YANG

1

*

1

Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University,

866# Yuhangtang Rd., Hangzhou, Hangzhou, 310058, China

2

Ningbo People’s Hospital, Ningbo, 315000, China

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