• No se han encontrado resultados

Hypromelose / polyethylene oxide (PEO) matrix tablets for oral sustained Aacyclovir release: formulation aspects and release behavior

N/A
N/A
Protected

Academic year: 2017

Share "Hypromelose / polyethylene oxide (PEO) matrix tablets for oral sustained Aacyclovir release: formulation aspects and release behavior"

Copied!
1
0
0

Texto completo

(1)

480 ISSN 0326-2383

KEY WORDS: ACV, Hypromelose, Hydrophilic matrix tablets, POE, Polymer gels. * Author to whom correspondence should be addressed. E-mail: hellen.stulzer@gmail.com

Latin American Journal of Pharmacy

(formerly

Acta Farmacéutica Bonaerense)

Lat. Am. J. Pharm.

30

(3): 480-6 (2011)

Original Article Received: April 23, 2010 Revised version: July 27, 2010 Accepted: July 29, 2010

Hypromelose / Polyethylene Oxide (PEO) Matrix Tablets

for Oral Sustained Acyclovir Release:

Formulation Aspects and Release Behavior

Débora D. VECHIA

1

, Fernanda M. BARBOZA

1

, Flavio L. BELTRAME

1

,

Carlos A. FRAGA

1

, Marcos A.S. SILVA

2

& Hellen K. STULZER

1,2

*

1

Laboratório de Química Farmacêutica e Controle de Qualidade,

Departamento de Ciências Farmacêuticas

Universidade Estadual de Ponta Grossa, Campus Uvaranas

-Av. General Carlos Cavalcanti, 4748 - CEP 84.030-900, Ponta Grossa, Paraná, Brazil.

2

Laboratório de Controle de Qualidade, Departamento de Ciências Farmacêuticas

Universidade Federal de Santa Catarina, Campus Universitário,

Trindade, CEP 88040-900, Florianópolis, Santa Catarina, Brazil.

Referencias

Documento similar

When Fampyra prolonged-release tablets are taken with food, the reduction in the area under the plasma concentration-time curve (AUC 0-∞ ) of fampridine is approximately 2-7% (10

In the social and affective aspects, evaluated variables were: habits of frequenting restaurants, participation in collective events, leisure activities, the

Scatter plot of Volumetric water content (A) and plug weight (B) versus Soil water potential and the parameters of the fitting function and the equation to transform plug weight

50 As the hollow+porous fibers present a higher outer surface roughness due to its increased surface porosity, their lower Ibuprofen release rate and damage associated to

PCA was applied to the correlation matrix constructed from the extraction percentages of acylated and non-acylated anthocyanins, ripeness degree, soluble solids content and cell

The application concerns an oral immediate release formulation (orodispersible tablets) and as indicated in the SmPC of the reference product: "tramadol/paracetamol

to a decrease in drug bioavailability, drug degradation, and/or production of toxic products. In the literature there are studies that have evaluated the

In particular, we characterize and evaluate an effective therapeutic polymeric PEGylated nanosystem for controlled pH-sensitive drug release on a breast cancer (MDA-MB-231) and two