Evaluation of the effect of drug solubility behaviour on the rate of release from the hydrophilic matrix system

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1867 ISSN 0326-2383

KEY WORDS: Extended release, Hypromellose K200M, Metoprolol Succinate, POLYOX WSR-303, Propra-nolol hydrochloride.

* Author to whom correspondence should be addressed. E-mail: santosh_narla@yahoo.com

Latin American Journal of Pharmacy

(formerly

Acta Farmacéutica Bonaerense)

Lat. Am. J. Pharm.

30

(9): 1867-71 (2011)

Short communication Received: May 5, 2011 Revised version: October 25, 2011 Accepted: October 25, 2011

Evaluation of the Effect of Drug Solubility Behaviour

on the Rate of Release from the Hydrophilic Matrix System

Santosh KUMAR NARLA

1

*, M.V.V NAGESWARA REDDY

2

& Chandramohan EAGA

3

1

Department of Pharmaceutical Sciences, JNTUH Campus, Hyderabad, India.

2

Aurobindo Pharma Limited, Hyderabad, A.P, India.

3

Genovo Development Limited, Bangalore, Karnataka, India.

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Related subjects : extended release