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Determination of meloxicam in human plasma administrated with four drugs by LC method: application to a pilot bioavailability study

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1883 ISSN 0326-2383

KEY WORDS:Meloxicam, Bioanalytical method, pharmacokinetic study, Reversed-phase liquid chromatography.

* Author to whom correspondence should be addressed. E-mail:leila.leal@nudfac.com.br

Latin American Journal of Pharmacy

(formerly

Acta Farmacéutica Bonaerense)

Lat. Am. J. Pharm.

30

(10): 1883-8 (2011)

Regular Article Received: August 18, 2011 Revised version: October 24, 2011

Accepted: October 25, 2011

Determination of Meloxicam in Human Plasma Administrated with

Four Drugs by LC Method: Application to a Pilot Bioavailability Study

Leila B. LEAL

1

*, Danilo C.G. BEDOR

1

, Elayne K.S. MELO

1

,

Eduardo J. OLIVEIRA

2

& Davi P. SANTANA

1

1

Núcleo de Desenvolvimento Farmacêutico e Cosmético – Universidade Federal de Pernambuco,

Rua Professor Arthur de Sá s/n, Cidade Universitária, CEP 50740-520, Recife, Pernambuco, Brasil.

2

Laboratório de Tecnologia Farmacêutica, Universidade Federal da Paraíba (LTF-UFPB), Brasil.

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