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HPLC method for assessment of in vitro and in vivo recovery of gatifloxacin using microdialysis

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467 ISSN 0326-2383

KEY WORDS:Gatifloxacin, High performance liquid chromatography, Microdialysis, No net flux, Probe recovery.

* Author to whom correspondence should be addressed. E-mail: ltasso@ucs.br

Latin American Journal of Pharmacy

(formerly

Acta Farmacéutica Bonaerense)

Lat. Am. J. Pharm. 30

(3): 467-72 (2011)

Original Article Received: July 5, 2010 Revised version: July 26, 2010 Accepted: July 27, 2010

HPLC Method for Assessment of

In Vitro

and

In Vivo

Recovery

of Gatifloxacin Using Microdialysis

Leandro TASSO

1,2

*, Clarissa BETTONI

1

&Teresa DALLA COSTA

1,3

1

Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia,

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

2

Universidade de Caxias do Sul, Caxias do Sul, RS, Brazil

3

Centro Bioanalítico de Medicamentos, Faculdade de Farmácia,

Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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