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IL 21 signaling pathway modulation in B lymphocytes by vitamin D in systemic lupus erythematosus

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Academic year: 2020

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Figure 1: Vitamin D supplementation protocol  in  patients  with  Systemic  Lupus  Erythematosus with hypovitaminosis D
Figure  2:  Serum  IL-21  levels  in  healthy  controls  and  in  SLE  patients. Serum IL-21 was analyzed by ELISA in 22 healthy controls  and  28  patients,  IL-21  was  only  detected  in  5  patients  and  no
Figure  3:  Serum  IL-21  levels  in  SLE  patients  before  and  after  supplementation
Figure 6: IL-21R expression on B cells from healthy controls and  SLE patients.  PBMC isolated from healthy patients and SLE patients  were  stained  with  FITC-anti-CD19  and  PE-anti-IL-21R,  fixed  and  acquired with BD FACSCalibur cytometer
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