Prospective registry of symptomatic severe aortic stenosis in octogenarians: a need for intervention.

Transgenic mice constitutively overexpressing human β3AR in the heart (c-hβ3tg) were protected from the development of HF in response to induced AS, and against

Percentage of subjects with moderate to severe mitral annulus calcification (MAC) and aortic valve calcification (AV) according to urinary phytate level tertiles (Low, <0.61μM,

VICs isolated from men’s AVs secreted higher amounts of the pro-angiogenic factors, VEGF-A, VEGFR1, IGFBP-2, and FGF-7, as well as the pro-lymphangiogenic factors, VEGF-C, VEGF-D,

Plk1(+/–) and Plk1( Δ/Δ) SM mice, as well as in wild-type mice treated with volasertib, 404. indicate further functions of Plk1 in the maintenance of

Important differences between the two analyses are present in term of overall freedom from SVD events. In our analysis at 10 years about 74 % of the population is free from

Immunohistochemical staining of the aortic root lesions showed increased expression of VCAM-1 protein, as well as a mild immunoreac- tivity for ICAM-1 in the vascular endothelium of

Visual inspection of intake and exhaust valves and valve seats of 8-valve engines revealed occurrence of surface damages produced not only by tribological

Boxplot graphs showing the frequencies of innate and adaptative cell subsets from peripheral blood (blue) and valvular infiltrate (orange). Frequencies were calculated from the