• No se han encontrado resultados

A Molecular Modeling Approach to Identify Novel Inhibitors of the Major Facilitator Superfamily of Efflux Pump Transporters

N/A
N/A
Protected

Academic year: 2020

Share "A Molecular Modeling Approach to Identify Novel Inhibitors of the Major Facilitator Superfamily of Efflux Pump Transporters"

Copied!
11
0
0

Texto completo

Loading

Figure

Figure 1. (a) 3D model structure of the NorA efflux pump from S. aureus, showing that both the N- N-and C-terminal domains are connected by XII α-helices N-and cytoplasmic loops
Figure 4. Binding mode of capsaicin (grey) and lead compound CID 44330438 (red) to the NorA efflux  pump ligand binding site

Referencias

Documento similar

The best results, in terms of dechlorination degree and selectivity to the target compounds, were obtained with the KOH derived catalyst, with a selectivity to ethane

Direct current (dc) electrical conductivity measurements were performed on different single crystals of compound 4 and pellets of compounds 3 and 4. The compounds were

At the same time, higher values of the quantum efficiency were found in the photocatalytic degradation of phenol, methyl 4-hydroxybenzoate and 4-chlorophenol with P25, whereas in

Astrometric and photometric star cata- logues derived from the ESA HIPPARCOS Space Astrometry Mission.

maltophilia, the SmeDEF efflux pump and the SmQnr protein, to the development of acquired quinolone resistance.. Comparisons were made of the apparent mutation frequencies

Upon Fenton oxidation of the four ILs tested hydroxylated compounds of higher molecular weight than the starting ILs, fragments of ILs partially oxidized and short-chain

antioxidant capacity mainly due to their content of phenolic compounds. UV-B samples early showed the highest TAC increments with levels 330. 47 % higher than CTRL samples at 24

of the behavior of the users of the buildings was found to be a concern with rising interest, and a modeling approach was proposed to take advantage of