Wnt/beta catenin pathway in the prefrontal cortex is required for cocaine induced neuroadaptations

We applied the criteria summarized in Table 2 for categorizing cortical types in human prefrontal areas and visual areas in the occipital lobe described above to the micrographs of

Canonical (Wnt- β-catenin) signalling promotes synapse stability, while non-canonical (Wnt-PCP) signalling favours synapse retraction; thus A β-driven synapse loss is mediated by

URI specifically localizes and inhibits WNT/  catenin signaling pathway in stem-cell-like label retaining (LR) cells, essential for organ regeneration following IR

The primase activity of PrimPol is required to bypass UV-induced lesions in vivo, as primase-null PrimPol versions with intact TLS polymerase activity failed to

Remarkably, mutation of all four Ser/Thr residues (P4m) of the epitope produced a protein that showed no shift in mobility in response to either Wnt3a or Wnt5a signaling

Importantly, we extended the study of 1,25(OH) 2 D 3 and Wnt3A action to primary cultures of human colon NFs and CAFs derived from CRC patients, and to IMR-90 human lung

In addition, in contrast to the effects observed in established colon carcinoma cell lines, 1,25(OH) 2 D 3 does not affect the expression of key genes of the Wnt/β-catenin

For a detailed study, we chose the PKP2 gene, which is con- sistently upregulated by Wnt3A in CCD-18Co cells and enco- des the protein Plakophilin-2, whose effect on Wnt signalling