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Studies of P2X4 receptor dynamics upon agonist activation by High Speed Atomic Force Microscopy and Molecular Dynamics simulations

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Figure 3. Simulation of free diffusing particles. (A) It is shown the trajectories of different particles  that  have  velocities  given  by  a  Gaussian  distribution
Table 1. CHARMM Force Field. Light blue spheres represent atoms that are connected by bonds (stick or  spring)
Figure 5. P2X4 receptor purification from TsA201 cells. (a) Western blot is showing a band in the  fraction elution with a molecular weight lower than 50 kDa
Figure 7. AFM topographic image of a single P2X4 receptor on a lipid bilayer.  (A) A 250 x 250  nm 2  image shows a P2X4 receptor composed of three blobs and a maximum height of about 4.5 nm
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