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Tumor Necrosis Factor α Regulates Glucocorticoid Synthesis in the Adrenal Glands of Trypanosoma cruzi Acutely Infected Mice The Role of TNF R1

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Academic year: 2020

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Figure 1. Changes in relative weight, TNF-R1 expression and morphology in endocrine glands from T
Table 2. Cytokine levels in plasma of mice undergoing acute T. cruzi infection. Plasma levels (pg/mL) WT TNF-R1 2/2 Tc-WT Tc-TNF-R1 2/2 TNF-a nd nd 588699* 29996324 &, # IL-6 8.565.1 55.167.1* 528668* 612681 & IL-1b 22.764.5 89.8610.8* 82.1615.7* 3
Figure 2. Hormonal variations in the HPA axis from T. cruzi - -infected mice. Plasma levels of corticosterone (mg/dl, panel A) and ACTH (pg/ml, panel B) in C57BL/6 mice acutely infected with T
Figure 3. Activation of NF-kB and AP-1 in adrenal gland during T. cruzi infection. Levels of NF-kB activity (OD 450/650, panel A) and activation of AP-1 (panel B) in nuclear extracts of adrenal glands from C57BL/6 mice acutely infected with T
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