Ficha del Directorio
Ficha de investigador
FRANCISCO JAVIER OLIVER POZO
Grupo de Investigación: ONCOLOGIA E INMUNOLOGIA MOLECULAR (Cod.: CTS434)
Departamento: Instituto de Parasitología y Biomedicina López-Neyra (CSIC-IPBLN). Biología Celular e Inmunología
Código: 22981
Producción 85
Artículos (74)
Libros (0)
Capítulos de Libros (4)
Tesis dirigidas (7)
Proyectos dirigidos 9
Proyectos (9)
Contratos (0)
Convenios (0)
Actividades 0
Evolución producción Tesis Capítu… Libros Artículos 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016 0.0 2.5 5.0 7.5 10.0 AñoProyectos en curso por año
Conve… Contr… Proye… 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 0 1 2 3 4 Año
Allogeneic adipose-derived mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by regulating self-reactive t cell responses and dendritic cell function.
Stem cells international Articulo 2017 Vasculogenic mimicry signaling revisited: focus on
non-vascular ve-cadherin. Molecular cancer Articulo 2017
Autophagy requires poly(adp-ribosyl)altion dependent
ampk nuclear export Cell death and differentiation Articulo 2016
Effect of poly¿adp(ribose) polymerase inhibition on
glioblastoma Tesisdoctoral 2015
Functional consequences for apoptosis by transcription elongation regulator 1 (tcerg1)-mediated bcl-x and fas/cd95 alternative splicing
Plos one Articulo 2015
Parp targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in pten¿mutant glioma
Oncotarget Articulo 2015
Interaction between parp-1 and hif-2 alpha in the hypoxic
response. Oncogene Articulo 2014
Parp targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in pten-mutant glioma
Oncotarget Articulo 2014
Targeting parp-1 in breast cancer: the paradigm of a dna repair-based therapeutic strategy
Descoberta, desenho e desenvolvimento no âmbito do programa iberoamericano-cyted
Capítulo de libro 2014 Growth and spontaneous differentiation of umbilical-cord
stromal stem cells on activated carbon cloth Journal of materials chemistry b Articulo 2013 Parp inhibition attenuates histopathological lesion in
ischemia/reperfusion renal mouse model after cold prolonged ischemia
The scientific world journal Articulo 2013 Parp-1 regulates metastatic melanoma through
modulation of vimentin-induced malignant
transformation. Plos genetics Articulo 2013
Parp-1 participates in metastasic melanoma through regulation of vascular plasticity and vimentin-induced malignant transformation
Plos genetics Articulo 2013
Parp-1 regulates metastatic melanoma through modulation of vimentin-induced malignant
transformation. Plos genetics Articulo 2013
Papel de parp1 y del procesamiento de poli(adp-ribosilación) en autofagia: regulaci¿¿on sobre la ruta de ampk/mtorc1
Instituto de parasitología y biomedicina lópez-neyra (csic-ipbln). biología celular e inmunología
Tesis
doctoral 2013 Poly(adp-ribose) signaling in cell death. Molecular aspects of medicine Articulo 2013 Targeting parp-1 in breast cancer: the paradigm of a dna
repair-based Cancer biomarkers Capítulode libro 2013
Umbilical-cord stromal stem cells grown and differentiation on an activated-carbon cloth: the importance of surface porosity
Journal of materials chemistry b Articulo 2013 . nitric oxide modulates hypoxia-inducible factor-1 and
poly(adp-ribose) polymerase-1 cross-talk in response to
hypobaric hypoxia Journal of applied physiology Articulo 2012
Efecto de la inhibición de parp-1 sobre angiogénesis,
metástasis y mimetismo vasculogénico en melanoma Tesisdoctoral 2012
metástasis y mimetismo vasculogénico en melanoma doctoral 2012 Ros-induced dna damage and parp-1 are required for
optimal induction of starvation-induced autophagy Cell research Articulo 2012 The importance of bystander effects in radiation therapy
in melanoma skin-cancer cells and umbilical-cord
stromal stem cells Radiotherapy and oncology Articulo 2012
Human umbilical cord stromal stem cell express cd10
and exert contractile properties Placenta Articulo 2011
Inhibition of poly (adp-ribose) polymerase-1 enhances
doxorubicin activity against liver cancer cells Cancer letters Articulo 2011 Nitric oxide modulates hypoxia-inducible factor-1 and
poly(adp-ribose) polymerase-1 cross-talk in response to hypobaric hypoxia.
Journal of applied physiology Articulo 2011 Poly(adp-ribose)-dependent regulation of snail1 protein
stability Oncogene Articulo 2011
Poly(adp-ribose)-dependent regulation of snail1 protein
stability. Oncogene Articulo 2011
Tela de carbón activo: biomateriales para la proliferación
de células mesenquimales Boletín del grupo español del carbón Articulo 2011 Inhibition of poly (adp-ribose) polymerase decreases
hepatocellular carcinoma growth by modulation of tumour-related gene expression
Journal of hepatology Articulo 2010
Inhibition of poly (adp-ribose) polymerase-1 enhances
doxorubicin activity against liver cancer cells Cancer letters Articulo 2010 Inhibition of poly (adp-ribose) polymerase decreases
hepatocellular carcinoma growth by modulation of
tumour-related gene expression. Hepatology Articulo 2010
Parp-1 modulation of brain hif-1 in vivo response to
hypoxia/reoxygenation is mediated by nitric oxide and fih Neurochemistry Articulo 2010 Activated carbon cloth as support for mesenchymal
stem cell growth and differentiation to osteocytes Carbon Articulo 2009
Parp-1 is involved in autophagy induced by dna damage Autophagy Articulo 2009 Poly(adp-ribose) polymerase-1 modulation of in vivo
response of brain hypoxia-inducible factor-1 to hypoxia/reoxygenation is mediated by nitric oxide and factor inhibiting hif
Journal of neurochemistry Articulo 2009 Poly[adp-ribose] polymerase-1 expression is related to
cold ischemia, acute tubular necrosis, and delayed renal
function in kidney transplantation Plos one Articulo 2009
Poly[adp-ribose] polymerase-1 expression is directly related to acute tubular necrosis, cold ischemia, and delayed renal function in kidney transplantation
Plos one Articulo 2009
Función de parp-1 en rutas de inestabilidad genómica e hipoxia: implicaciones en el control tumoral
Instituto de parasitologia y biomedicina lopez neyra (ipbln)(delegación del c.s.i.c.en andalucía). biología celular e inmunología
Tesis
doctoral 2008 Parp-1 modulates deferoxamine-induced hif-1alpha
accumulation through the regulation of nitric oxide and
oxidative stress. Journal of cellular biochemistry Articulo 2008
Parp-1, nueva diana el el tratamiento del carcinoma hepatocelular
Instituto de parasitologia y biomedicina lopez neyra (ipbln)(delegación del c.s.i.c.en andalucía). biología celular e inmunología
Tesis
doctoral 2008 Poly(adp-ribose)polymerase-1 (parp-1) in carcinogenesis:
potential role of parp inhibitors in cancer treatment Clinical & translational oncology Articulo 2008 Quantitative detection of methylated esr1 and 14-3-3-?
gene promoters in serum as candidate biomarkers for diagnosis of breast cancer and evaluation of treatment efficacy
Cancer biology & therapy Articulo 2008 Interaction between atm and parp-1 in response to dna
damage and sensitization of atm deficient cells through parp inhibition
Bmc molecular biology Articulo 2007
Modulation of transcription by parp-1: consequences in
carcinogenesis and inflammation. Current medicinal chemistry Articulo 2007 Therapeutic effect of a poly(adp-ribose) polymerase-1
inhibitor on experimental arthritis by downregulating inflammation and th1 response.
Plos one Articulo 2007
Inhibition of poly(adp-ribose) polymerase modulates tumor-related gene expression, including hypoxia-inducible factor-1 activation, during skin carcinogenesis
Cancer research Articulo 2006
Papel de parp-1 en procesos de muerte celular inducida por el tratamiento con el antineoplásico doxorrubicina
Universidad de granada. radiología y medicina física
Tesis
doctoral 2006 Early and late skin reactions to radiotherapy for breast
cancer and their correlation with radiation-induced dna damage in lymphocytes.
Breast cancer research Articulo 2005 Involvement of poly (adp-ribose) polymerase in the
cellular response to dna damage
Poly (adp-ribose) polymerase and apoptosis
Capítulo de libro 2005 Modulación por poli(adp-ribosa) polimerasa1- de la
expresión génica durante la carcinogénesis epidérmica
Tesis
doctoral 2005 Parp inhibition sensitizes p53-deficient breast cancer
cells to doxorubicin-induced apoptosis Biochemical journal Articulo 2005
Parp-1-dependent 3-nitrotyrosine protein modification
after dna damage Journal of cellular biochemistry Articulo 2005
Role of poly (adp-ribose) polymerase in kidney transplant and its relationship with delayed renal function.
multivariate analysis. Transplantation proceedings Articulo 2005
Correlation of morphological findings with functional reserve in the aging donor: role of the poly (adp-ribose) polymerase
Transplantation proceedings Articulo 2004 Crosstalk between parp-1 and nf-kappa b modulates the
promotion of skin neoplasia Oncogene Articulo 2004
Transcription regulation of tnf-alpha-early response genes poly (adp-ribose) polymerae-1 in murine hearth
endotelial cells Nucleic acids research Articulo 2003
Parp-1 modifies the effectiveness of p53-mediated dna
damage response Oncogene Articulo 2002
Radiación, adn, cromatina y respuesta a la terapéutica Oncología molecular Capítulode libro 2002 Role of poly(adp-ribose) polymerase in the inflammatory
response Inmunologia Articulo 2002
Apoptosis of haematopoietic cells upon thymidylate synthase inhibition is independent of p53 accumulation and cd95-cd95 ligand interaction
Biochemical journal Articulo 2001
Interplay of parp-1 and p53 in cell cycles checkpoints
and tumorigenesis Embo journal Articulo 2001
A dual approach in the study of poly (adp-ribose)
polymerase: in vitro random mutagenesis and generation of deficient mice.
Defective nf-kb activation and resistance to septic shock
in poly (adp-ribose) polymerase (parp) deficient mice Embo journal Articulo 1999 Involvement of poly(adp-ribose) polymerase in base
excision repair. Biochimie Articulo 1999
Poly (adp-ribose) polymerase in dna damage response,
apoptosis and disease American journal of human genetics Articulo 1999
Deficient dna repair in poly (adp-ribose) polymerase null
mice Nucleic acids research Articulo 1998
La poly (adp-ribose) polymerase : un facteur de survie Medicine et science Articulo 1998 Poly (adp-ribose) polymerase is required for the
maintenance of genomic integrity during base excision
repair Nucleic acids and molecular biology Articulo 1998
Role of parp and parp cleavage in apoptosis: lesson from
an uncleavable mutant. Journal of biological chemistry Articulo 1998
Overexpression of a heterologous thymidine kinase delays apoptosis induced by factor deprivation and inhibitors of deoxynucleotide metabolism
Journal of biological chemistry Articulo 1997 Requirement of poly (adp-ribose) polymerase in recovery
from dna damage in mice and in cells.
Proceedings of the national academy of sciences of the united states of
america Articulo 1997
An apoptotic endonuclease activated either by
decreasing ph or by increasing calcium Journal of cell science Articulo 1996 Effects of starvation, diabetes and carbon tetrachloride
intoxication on rat kidney cortex and liver pyruvate carboxylase levels
Archives of physiology and
biochemistry Articulo 1996
Regulation of the salvage pathway of deoxynucleotides synthesis in apoptosis induced by growth factor deprivation
Biochemical journal Articulo 1996
Citrate inhibition of rat-kidney cortex
phosphofructokinase Molecular and cellular biochemistry Articulo 1994
Citrate inhibition of rat-kidney cortex
phosphofructokinase Molecular and cellular biochemistry Articulo 1993
Effects of amp and fructose 2,6-bisphosphate on fluxes between glucose-6-phosphate and triose-phosphate in
renal cortical extracts Journal of biological chemistry Articulo 1993
Regulation of rat-kidney cortex fructose-1,6-bisphosphatase activity. i. effects of fructose-2,6-bisphosphate and divalent cations.
The international journal of
biochemistry & cell biology Articulo 1993 Regulation of rat-kidney cortex
fructose-1,6-bisphosphatase activity. ii. effects of adenine nucleotides.
The international journal of
biochemistry & cell biology Articulo 1993 Distribution of pyruvate carboxylase along the rat
nephron: an immunological and enzymatic study Kidney international Articulo 1991 Efecto de los cationes divalentes sobre la actividad
fructosa 1,6-bisfosfatasa purificada de corteza renal de rata.
Ars pharmaceutica Articulo 1991
Kinetic characterization of phosphofructokinase isolated from rat kidney cortex
Comparative biochemistry and
physiology. part b, biochemistry &
molecular biology Articulo 1991
Determinación de los coeficientes de control de flujo en
un tramo acotado de la ruta glucolítica Ars pharmaceutica Articulo 1990
Purification and characterization of pyruvate carboxylase
from rat-kidney cortex Biochemical archives Articulo 1990
Stimulation of mitochondrial pyruvate transport in rat
Actividades 0
Colaboradores
JOSÉ MARIANO RUIZ DE ALMODOVAR RIVERA
(28)
FRANCISCO DAVID MARTÍN OLIVA
(14)
JOSÉ ANTONIO MUÑOZ GÁMEZ
(13)
MARIA DEL MAR SOLA ZAPATA
(12)
RAFAEL SALTO GONZALEZ
(12)
ALBERTO MANUEL VARGAS MORALES
(11)
FRANCISCO J. O'VALLE RAVASSA
(11)
MARÍA ISABEL RODRÍGUEZ LARA
(11)
ANDREINA CECILIA PERALTA LEAL
(9)
ARIANNYS GONZALEZ FLORES
(8)
JOSE MANUEL RODRIGUEZ VARGAS
(8)
JARA MAJUELOS MELGUIZO
(7)
MARIA ISABEL NUÑEZ TORRES
(7)
ROSA QUILES PEREZ
(6)
VIRGÍNEA DE ARAUJO FARIAS
(6)
LAURA MARÍA LÓPEZ JIMÉNEZ
(5)
JOSE LUIS LINARES FERNÁNDEZ
(4)
Santiago Serrano Sáenz
(4)
ANGELES RUIZ EXTREMERA
(3)
CARLOS MORENO CASTILLA
(3)
MERCEDES VILLALOBOS TORRES
(3)
ANA BELÉN MARTIN ÁLVAREZ
(2)
ANTONIO OSUNA ORTEGA
(2)
DAVID AGUILAR PEÑA
(2)
FRANCISCO JAVIER SALMERON ESCOBAR
(2)
1 Efecto de vecindad (bystander) tras radioterapia de modelos de tumorexperimental y de tejido sano Proyecto 1/1/13 12/31/15 2 Modulación por parp-1 de la agresividad tumoral: papel en la respuesta hipóxica yen la transición epitelio mesénquima (emt). Proyecto 1/1/10 12/31/12 3 Melanoma maligno: estudio molecular y preclínico de la función de parp en elcontrol de la angiogénesis tumoral durante la hipoxia Proyecto 1/1/08 12/31/11 4 Poli(adp-ribosa)polimerasa-1: una nueva diana anti-angiogénica en la terapiaantineoplásica Proyecto 11/30/06 9/30/09 5 Nuevas funciones de poli(adp-ribosa) polimerasa-1 en la señalización y en elcontrol de la respuesta celular durante el daño genotóxico Proyecto 1/1/04 12/31/06 6 Regulación de la respuesta inflamatoria por poli(adp-ribosa) polimerasa-1: efectossobre la expresión génica y el daño oxidativo Proyecto 3/1/05 12/31/05
7 Inflamación y daño articular. Proyecto 1/1/03 12/31/05
8 Interacción entre parp y atm en la respuesta a daños genotóxicos Proyecto 1/1/02 12/31/03 9 Poli(adp-ribosa)polimerasa-1: una nueva diana anti-angiogénica en la terapia
antineoplásica Proyecto 10/1/07
Titulo proyecto Tipo Inicio Fin
