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( ) Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6 Aza Analogues of Angucyclinones

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Figure

Figure 1. Some examples of natural angucyclinones.
Figure 2. Chemical structures of (-)-shikimic acid and 6-aza-angucyclinone derivatives
Figure 3. Major HMBC correlations observed for compound 16b. The 3 J HC and 2 J HC correlations are shown in blue and red, respectively.
Figure 4. Molecular structure of compound 19c. Thermal ellipsoids are shown with 30% probability
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