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Liquid extracorporeal carbon dioxide removal: use of THAM (tris hydroxymethyl aminomethane) coupled to hemofiltration to control hypercapnic acidosis in a porcine model of protective mechanical ventilation

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Academic year: 2020

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Figure 1. Experimental design for THAM+HF group. The figure describes the four protocol periods, the timeline, and  the main events
Figure 3. Extracorporeal CO 2  removal by THAM cou- cou-pled with hemofiltration. Vertical broken line at T18  indicate the end of THAM infusion
Figure 5.  Evolution  of  the  osmolality.  Vertical  bro- bro-ken lines at T0 and T18 indicate the start and the  end of THAM infusion, respectively
Table S1. Hematologic, hepatic and biochemical laboratory data Variable Group T0 T6 T12 T18 T24 Hemoglobin   (gr·dL -1 ) [7.1-12] THAM+HF 7.4 (7.3, 8.3) 8.3 (7.6, 8.9) 8.1 (7, 8.5) 8.5 (6.8, 8.7) 7.5 (5.7, 9.3) Control  7.3 (6.8, 7.7) 8.4 (7.3, 9) 8.6 (7.6

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