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TítuloSenescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype

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Academic year: 2020

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Figure

Fig. 1 Expression of p16 and NANOG in ST. a IHC detection of p16 and NANOG in normal, OA and RA ST (Bar 50 μm)
Fig. 2 Analysis of senescence in 14-day SF cultures. a SA- β-gal activity and DAPI staining
Fig. 3 Analysis of senescent markers and SASP mediators in stress- induced senescent SF
Fig. 4 Effect of fenofibrate treatment in TNF α-induced senescent SF. 14-day senescent (SEN) and control (CT) SF were treated with fenofibrate (FB, 25 μM) for 72 h
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