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Synthesis and cytotoxic activity of tri acyl ester derivatives of uridine in breast cancer cells

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Figure

Figure 1. Reaction scheme for the uridine tri-esterified derivative formation by Steglich  esterification method and with anhydride acid.
Table 1.  1 H-NMR and  13 C-NMR signals of acetonide, C1, and C2 compounds Mass C6 (DMSO d6) C1 (DMSO d6) C2 (DMSO d6) Position δ H (ppm), mult  (Integ), J(Hz) δ C (ppm), Integ δ H (ppm), mult (Integ), J(Hz) δ C (ppm), Integ δ H (ppm), mult (Integ); J(Hz)
Figure 2. Cell viability of triesterified derivatives (C1-C4,  assessed compounds) with 1μM, 10μM and 100μM  concen-trations during 48 hours

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