Melatonin counteracts changes in hypothalamic gene expression of signals regulating feeding behavior in high fat fed rats
Texto completo
Figure
Documento similar
Right and left cortical and hippocampal mRNA expression of SIRT1 in 18-month-old rats in control (non-treated) conditions, after treatment with a daily dose of melatonin (10 mg/kg
Since melatonin inhibits the growth of C6 cells, and this indoleamine has been demon- strated to be capable of decreasing aromatase expression and activity in these cells, the aim
The Panel had no information about plasma levels of the hydrolysis products of aspartame in rats given very high doses of the sweetener, as in the ERF study, but it is possible
In conclusion, the circulating levels of the novel insulin- like adipokine ISM1 are significantly higher in pubertal chil- dren with obesity and are associated with BMI Z-score and fat
Changes in serum IL-15 levels at 4 and 8 weeks as compared with baseline values were directly associated with changes in body weight, BMI, fat-free mass, and muscle mass
In agreement with the observed changes in hepatic SREBP-1c expression in liver, central leptin blunted the up- regulation of the mRNA levels of ACC, FAS, and SCD-1 elicited by the
On the other hand, we addressed the role of GRK2 in the heart of adult (9 month) mice or of mice fed with high-fat diet, two conditions known to promote insulin resistance. In
Although, as mentioned above, no significant changes have been seen in IRS-2 levels with aging or food restriction, the reported increase of SOCS-3 expression in aged rats (10) may