Role of the Wnt receptor Frizzled 1 in presynaptic differentiation and function

Canonical (Wnt- β-catenin) signalling promotes synapse stability, while non-canonical (Wnt-PCP) signalling favours synapse retraction; thus A β-driven synapse loss is mediated by

Remarkably, mutation of all four Ser/Thr residues (P4m) of the epitope produced a protein that showed no shift in mobility in response to either Wnt3a or Wnt5a signaling

In addition, in contrast to the effects observed in established colon carcinoma cell lines, 1,25(OH) 2 D 3 does not affect the expression of key genes of the Wnt/β-catenin

For a detailed study, we chose the PKP2 gene, which is con- sistently upregulated by Wnt3A in CCD-18Co cells and enco- des the protein Plakophilin-2, whose effect on Wnt signalling

Even though the 1920s offered new employment opportunities in industries previously closed to women, often the women who took these jobs found themselves exploited.. No matter

 The expansionary monetary policy measures have had a negative impact on net interest margins both via the reduction in interest rates and –less powerfully- the flattening of the

Jointly estimate this entry game with several outcome equations (fees/rates, credit limits) for bank accounts, credit cards and lines of credit. Use simulation methods to

In our sample, 2890 deals were issued by less reputable underwriters (i.e. a weighted syndication underwriting reputation share below the share of the 7 th largest underwriter