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Determination of ibudilast in rabbit plasma by liquid chromatography-mass spectrometry and its application

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2065 ISSN 0326-2383

KEY WORDS: Ibudilast, LC-MS, Pharmacokinetics, Rabbit plasma. * Author to whom correspondence should be addressed. E-mail:hulufeng79@sina.com # These authors contributed equally to these work.

Latin American Journal of Pharmacy

(formerly

Acta Farmacéutica Bonaerense)

Lat. Am. J. Pharm.

30

(10): 2065-9 (2011)

Short communication

Received: October 22, 2011 Accepted: October 28, 2011

Determination of Ibudilast in Rabbit Plasma by

Liquid Chromatography-Mass Spectrometry and its Application

Cheng DING

1#

, Wei DONG

2#

, Fangfang YANG

1

, Wei SUN

3

, Xiaole CHEN

3

,

Jianshe MA

4

, Xianqin WANG

3

& Lufeng HU

1

*

1

The First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, China

2

The First Clinical Medical College of Wenzhou Medical College, Wenzhou 325000, China

3

Analytical and Testing Center of Wenzhou Medical College, Wenzhou 325035, China

4

School of Basic Medical Sciences of Wenzhou Medical College, Wenzhou 325035, China

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