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Functional impact of polymorphic inversions in the human genome

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Academic year: 2017

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Figure

Figure 1 - Classification of inversions – Left panel contains schematic representations of a pericentric (top) and recurrent (right) inversion event in the evolutionary history of species A,B,C
Figure 2 – Genomic rearrangements mediated by NAHR – Top panel: (a and b) Interchromosomal, intrachromosomal, or intrachromatid NAHR between directly orientated repeats causes deletion and/or duplication of the intervening sequence
Figure 3 - Schematic diagram showing the suppression of recombination in an inversion heterozygote - Two loci segregate for the alleles (A, a) and (B, b)
Figure 4 – Suppression of recombination - Left, inversion causing chromosomal loop during meiosis in inversion heterozygote
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