Analytical method validation for in vitro permeation of Calendula officinalis L. gel

925 ISSN 0326-2383

KEY WORDS:Analytical method validation, Calendula officinalisL., In vitrocutaneous permeation, Rutin.

* Author to whom correspondence should be addressed. E-mail: carrera@ufpa.br

Latin American Journal of Pharmacy

(formerly

Acta Farmacéutica Bonaerense)

Lat. Am. J. Pharm. 30

(5): 925-30 (2011)

Regular Article Received: August 16, 2010 Revised version: November 25, 2010 Accepted: Decem ber 2, 2010

Analytical Method Validation for

In Vitro

Permeation

of

Calendula officinalis

L. Gel

Kariane M. NUNES

_{, Elanne S. BANDEIRA}

_{, Eliana F. OZELA}

_,

Wagner L.R. BARBOSA

_{, Roseane M. RIBEIRO-COSTA}

_{, José O.C. SILVA JÚNIOR}

_*

1

_{Laboratory of Pharmacotechnical Research and Development, College of Pharmacy,}

Federal University of Pará, PA, Brazil

2

_{Laboratory of Quality Control of Medicines, College of Pharmacy,}

Federal University of Pará, PA, Brazil

3

_{Laboratory of Phytochemistry, College of Pharmacy, Federal University of Pará, PA, Brazil}