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Angiotensin II receptor type 1 blockade decreases CTGF/CCN2 mediated damage and fibrosis in normal and dystrophic skeletal muscles

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Academic year: 2020

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Fig. 1 Blocking of AT-1 receptor decreases CTGF-dependent pro-fibrotic activity in skeletal muscle cells
Fig. 2 Angiotensin II receptor type 1 blockade decreases CTGF-induced damage and collagen content in tibialis anterior muscle
Figure 6B shows the results of quantitative analysis of these experiments. These results suggest that the induction of TGF- ␤ signalling is related to the use of the adenovirus rather to the specific expression of CTGF.
Fig. 4 Tibialis anterior muscle fibrosis induced by CTGF is prevented by blocking Angiotensin II Receptor Type 1
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