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Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus

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Academic year: 2020

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Fig. 1. G αi1 and Gαi3 DKO blocks BDNF-induced Akt –mTORC1 and Erk activation in MEFs
Fig. 2. G αi1 and Gαi3 are required for BDNF- BDNF-induced Akt –mTORC1 and Erk activation in MEFs
Fig. 3. G αi1/3 are required for the TrkB adaptor complex formation. (A and B) WT and G αi1/3-DKO MEFs were treated with BDNF (25 ng/mL) for 5 min, and the association among TrkB, G αi3, and adaptor proteins was tested by the immunoprecipitation  as-say
Fig. 4. G αi1/3 are required for BDNF-induced signal- signal-ing and TrkB adaptor complex formation in cerebellar granule neurons
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