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Extended Kalman filter estimates the contour length of a protein in single molecule atomic force microscopy experiments

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Academic year: 2020

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FIG. 1. 共Color online兲 Single molecule AFM implementation of a KF, for the measurement of the contour length of a protein
FIG. 2. 共Color online兲 Mechanical properties of the AFM cantilever and of an extending polyprotein
FIG. 3. 共Color online兲 Analysis of the extended KF implementation. 共a兲 Simulated data created for the purpose of examining the behavior of the observer, generated by stepwise changes in the contour length and utilizing the same system model described in th
FIG. 4. 共Color online兲 Experiments with ubiquitin polyproteins at an exten- exten-sion rate of 400 nm/s produced 190 sawtooth traces for analysis

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