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Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system

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Academic year: 2020

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Figure

FIGURE 1 | Molecular description of hMPV and the role of viral proteins in the evasion of the immune response
FIGURE 2 | Toll-like receptors (TLRs) and their role in the evasion of the immune response induced by hMPV
FIGURE 3 | Effects of hMPV proteins on signaling pathways. Once the viral particle has fused with the plasmatic membrane, the viral RNA is delivered to the cytoplasm and recognized by MDA5 or RIG-I (PRRs), activating the IRF3 and NF-κB pathways through TRA

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