Endoplasmic reticulum stress independent activation of unfolded protein response kinases by a small molecule ATP mimic

A broad band of the expected molecular mass that was recognized by the anti-E3 antibody was also observed after Western blot analysis of histidine- tagged proteins obtained from

These heterogeneous results raise questions about the functional role of GPCR desensitization during directed migration, and suggests that the global effect of GRK2

5 Recently, we described that Chk1 and Atr1, two DNA-damage checkpoint kinases, were activated in response to the formation of b-heterodimer and that this activation resulted in

Several tumor-suppressors have been shown to be excluded from the cell nucleus in cancer cells by the nuclear export receptor CRM1 and abnormal expression of CRM1 is

Sigma54 dependent promoters Small molecule binding. Oligomerization

Transduction of hematopoietic Ba/F3 cells with retroviral vectors carrying BCR-JAK2 induced IL-3-independent cell growth, constitutive activation of the chimeric protein as well

In this review, we have highlighted the ER stressors that activate the UPR and subsequently EMT, suggesting that the UPR may be an additional upstream signal for the induction of

interferon, IRF: interferon regulatory factor, iJAK: inhibitor of Janus kinases, MAS: macrophage activation syndrome, MAVS: mitochondrial antiviral proteins, MDA5: