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Genome wide identification of new Wnt/beta catenin target genes in the human genome using CART method

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Academic year: 2020

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Figure 1 Number of CART trees that declare a gene to be a Wnt/
Figure 2 Gene Ontology enrichment for training and proposed Wnt/β-catenin pathway targets
Figure 3 Classic structure of a CART tree. The first node of the tree is subdivided into two finer nodes depending on whether v1 is lower than c1
Figure 4 General structure of the proposed method. We trained 1,500 CART trees using 66 known target genes marked as black dots and two groups of 8,000 randomly chosen genes from a list of 15,476 genes in the human genome
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