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Selective cytoprotective effect of histamine on doxorubicin induced hepatic and cardiac toxicity in animal models

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Academic year: 2020

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Figure 1. Histamine decreases doxorubicin-induced cardiotoxicity and hepatotoxicity in rats and mice
Figure 3. Histamine alleviates doxorubicin-induced cytotoxic and oxidative damage in a rat's liver
Figure 4. Doxorubicin and histamine effects on TBARS levels of H4R − / − mice compared with WT Balb/c mice
Figure 5. Histamine enhances anti-proliferative properties of doxorubicin in vitro. (a) Proliferation was evaluated by the clonogenic assay in human TNBC MDA-MB-231 cells treated with Dox (0.01 –10 nM) in the absence (closed circles) or presence (open circ
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