TítuloMitochondrial DNA haplogroup H as a risk factor for idiopathic dilated cardiomyopathy in Spanish population

Detection of Trypanosoma cruzi DNA in blood by PCR is associated with Chagas cardiomyopathy and disease severity.. Eur J Heart

The formation of mitochondrial reactive oxygen and nitrogen species may lead to endothelial dysfunction by the activation of the vascular and phagocy- tic NOXs through protein kinase

A central role in this attenuation is played by the mitochondrial transcription termination factor (mTERF), a DNA-binding protein that protects a 28 bp region within the tRNA

ΔCm, mitochondrial membrane potential; AMPK, AMP-activated protein kinase; ERK 1/2, extracellular signal-regulated kinase 1/2; IF1, ATPase inhibitory factor 1; IF1 KO , IF1

Key words: Drugs of abuse; senescence; mitochondrial DNA; stem/progenitor cell proliferation; lipofuscin..

The overexpression of IF1 in HCT116 cells (Figure 1C) resulted in decreased oxidative phosphorylation (OSR) (Figure 1D), mitochondrial hyperpolarization (Figure 1E) and a

In this review we will briefly summarize: (i) the sites of production, mechanism of action and signaling pathways that are activated by ROS and (ii) the role of the mitochondrial H

More recently, we have described that over-expression of IF1 in cells with negligible content of the protein results in the inhibition of the ATP synthetic activity of the H +