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BAX inhibitor 1 regulates autophagy by controlling the IRE1 alpha branch of the unfolded protein response

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Academic year: 2020

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Figure 1 Increased accumulation of autophagosomes and lysosomes in BI-1-deficient cells
Figure 3 BI-1 deficiency increases cell survival under nutrient starvation conditions
Figure 6 BI-1 controls autophagy activation in vivo in Drosophila melanogaster. (A) The expression of dBI-1 was knocked down in Drosophila melanogaster
Figure 7 Enhanced LC3-II levels in the liver and kidney of bi-1-deficient mice. (A) The levels of LC3, Atg5/Atg12 complex, Beclin-1, Bcl-2, Bcl- Bcl-X L , IRE1a and Hsp90 were monitored in liver protein extracts of bi-1 þ / þ and bi-1 / at 6-month-old mi

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