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7 Nitroindazole down regulates dopamine/DARPP 32 signaling in neostriatal neurons in a rat model of Parkinson's disease

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Academic year: 2020

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Figure

Fig. 1. Striatal injections of 6-OHDA causes a mild parkinsonism in rats which is reverted by 7-NI treatment
Fig. 4. Intrastriatal 6-OHDA injections increases phospho-Thr34-DARPP-32 in the dorsolateral striatum and is reverted by 7-NI
Fig. 5. Correlations of the changes in the dorsolateral striatum after 6-OHDA neuro- neuro-degeneration
Fig. 6. Model of the role of NO signaling in the short-term facilitation of dopaminergic transmission in control and parkinsonism

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