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The mitochondrial complex I activity is reduced in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function

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Figure

Figure 1. Mitochondrial complex I in-gel activity (IGA) of CFDE and CFDE/6RepCFTR cells
Figure 2. Mitochondrial complex I in-gel activity (IGA) of IB3-1 and S9 cells. A: IGA of mitochondrial extracts from Control and  CFTR-stimulated IB3-1 and S9 cells (IBMX-isop-cAMP), adding 200 mM cAMP, 10 mM isoproterenol, 200 mM IBMX, for 24 h
Figure 6 summarizes this idea and the possible consequences of a reduced mCx-I activity, according to know relationships extracted by the software Pathway Studio (www.

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