New clinical advances in immunotherapy for the treatment of solid tumours

However, the fact that the activity of JNK signalling in eiger mutant regenerating discs is mostly restricted to the wound edges, though we found apoptotic cells far away from

SECTION 3 - The role of RINGO proteins in the brain 123 RingoA mRNA is expressed in neural stem cells and proliferating progenitor cells 123 Analysis of neural stem cells

Thus, chronic tumor associated antigen exposure in cancer can lead to high levels of PD-1 expression on T-cells, which can interact with PD-L1 expressed on cancer cells,

The main goal of this thesis was to study the effects of the transplantation of human neural stem cells (hNSCs), specifically hVM1 clone 32 cells, in an in vivo PD mouse model using

Effectiveness of immunosuppression minimisation, conversion or withdrawal strategies in paediatric solid organ and haematopoietic stem cell transplantation: a protocol of

The results of our study support the latter hypothesis by showing that: i) PD-like pathology progression in vivo depends on cell-to-cell transmission between neurons of the

This is in sharp contrast with the results obtained in [14] for the non rectilinear motions of the linear drag (no collision in finite time, energy which goes to −∞ as t → +∞) and

An increase in HIF-1α (Hypoxia-Inducible Factor-1-alpha) is associated with PD-L1 overexpression suggesting that hypoxic environments, typical of tumour microenvironments,