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Structural determinants of 5′,6′ epoxyeicosatrienoic acid binding to and activation of TRPV4 channel

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Figure 2.  Thermophoretic analysis of the TRPV4-EET interaction. (a) Typical signal of a microscale  thermophoresis (MST) experiment showing the thermophoretic movement (induced by infrared laser  activation, arrow) of the GFP-labeled TRPV4 WT or K535A mut
Figure 4.  TRPV4-K535A channel loses activation by 5′,6′-EET not by heat or GSK1016790A agonist

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