The impact of transposable element activity on therapeutically relevant human stem cells

Importantly, silencing of endogenous HIF2 a resulted in a marked repression of mTORC1 activity and SLC7A5 expression in 786-O VHL-deficient cells when cells were cultured

SECTION 3 - The role of RINGO proteins in the brain 123 RingoA mRNA is expressed in neural stem cells and proliferating progenitor cells 123 Analysis of neural stem cells

human mesenchymal stem cells from bone marrow and adipose tissue under xeno-free conditions for cell therapy. Stem Cell

To analyze the effects of PA2.26 expression on the phenotype of human epithelial cells, we transiently transfected HeLa carcinoma cells and HaCaT immortalized keratinocytes with

Human cancer cells show predominant expression of NANOGP8, whereas pluripotent cells (embryonic stem cells and embryonal carcinoma cells) express the NANOG variant

In humans, telomerase activity is restricted to embryonic development, embryonic stem (ES) cells, germ cells, adult stem cell compartments, certain types of Figure 3:

A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice.. The

Consequently, in this thesis we have generated two cellular models, a mouse model based on NURR1 overexpression in neural stem cells, and a human model based