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Silencing of tumor suppressor genes RASSF1A, SLIT2, and WIF1 by promoter hypermethylation in hereditary breast cancer

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Academic year: 2020

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Figure

Table 1. MS-PCR Features and Primer Sequences for Each Analyzed Gene Promoter
Figure 2. Products amplified by methylation specific PCR (MS-PCR) of (a) RASSF1A, (b) SLIT2, and (c) WIF1 promoter regions
Table 2. Frequency of CpG Sites Methylated at Each Promoter, Amplified by MSPCR for Methylated DNA
Figure 3H and I (T44 and T17) show a weak SLIT2 staining. In the methylation analysis T44 (H) gave only UM product and T17 (I) UM and M products.

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