• No se han encontrado resultados

Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases

N/A
N/A
Protected

Academic year: 2020

Share "Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases"

Copied!
13
0
0

Texto completo

Loading

Figure

Fig. 1. ICs stimulate pDCs by TLR9 ligation after endocytosis mediated by FcγRs. Extracellular DAMPs such as self-DNA/self-RNA needs to be transported into PRRs (pathogen recognition receptors)/TLR3, 7–9 containing endosomes to fully activate pDCs leading
Fig. 3. Most used strategies to induce tolDCs. Pharmacologic intervention to generate tolDCs could be achieved mainly by NFκB inhibition (Dex—dexamethasone, VD3—vitamin D3, aspirin, RAPA—rapamycin, BAY11-7082, CoPP—cobalt protoporphyrin, rosiglitazone) whi

Referencias

Documento similar

The performance and durability of PEM fuel cells significantly depend on variations in the concentrations of hydrogen and oxygen in the gas channels, water activity in the

Human cancer cells show predominant expression of NANOGP8, whereas pluripotent cells (embryonic stem cells and embryonal carcinoma cells) express the NANOG variant

Interestingly, when re-evaluated after one year and when patients were receiving treatment with oral MTX with or without low-dose prednisone, the frequencies of circulating Th17 and

The regulation of more than thousand vitamin D target genes in colon carcinoma cells, normal stem cells, cancer stem cells, stromal NFs and CAFs as well as immune cells of the

A pool of Hdac6 +/+ and Hdac6 -/- spleens non-infected was used as a control sample without infection (NI). Control vehicles and autophagy markers. A) Total CFUs at 0 and 6 hpi in

To unequivocally assess the role of HIF1 a in aspartate metabolism, we restored HIF1a expression by transduction of a wild-type version of HIF1 a in 786-O cells (786-O-HIF1 a cells)

OSKM expression has two mutually exclusive outcomes: in some cells it induces dedifferentiation to form induced pluripotent stem (iPS) cells, in other cells it

To provide a more general overview of the path- ways modified by productive interaction with T cells, differentially expressed genes were analyzed using Ingenuity Pathway