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Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells

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Academic year: 2020

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Figure

Fig 1. atRA enhances the generation of TGF-β1/IL2-induced Treg cells from naive T cells
Fig 2. RAPA alone or in combination with atRA does not enhance the generation of Treg cells from naive T cells in short-time cultures
Fig 3. TGFβ1, atRA and RAPA have diverse effects on the induction of CD45RA, CD62L, CXCR4, CCR9 and β7 expression on Treg cells.
Fig 4. Treg cells induced in the presence of atRA and/or RAPA are highly methylated in the CNS2 region
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