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Pharmacognosy 2 Minia University Third semester Faculty of Pharmacy

Clinical Pharmacy program Pharmacognosy department Final exam (2.12.2018)

Question I Encircle the possible correct answer:

1- Isoquinoline alkaloids are the main A.C. :

a) Senega root. b) Liquorice root.

c) Saquel Hamam. d) Jalap root.

e) Wolf’s bane root.

2- Wolf’s bane root is characterized by all the following except:

a) It belongs to family Ranunculaceae.

b) It has stellate phloem abnormal structure.

c) Diterpene ester alkaloids are the main active constituents.

d) It induces arrythmia.

e) Hydrocortisone can be used as antidot for its poisoning.

3- One of the following drugs can be used in insomnia:

a) Sweet wood. b) Snake root. c) Gentiana root.

d) Sarsaparilla root. e) Indian Snake root 4- Concerning senegin, all of the following characters are true except:

a) They are steroidal saponins. b) Used in chronic bronchitis.

c) They are present in senega root.

d) They give sternutatory after hydrolysis.

e) It gives positive with Salkowiski`s test.

5- The Hypoglycemic effect of gineng is due to:

a) It maked bone-marrow mitosis

b) It enhances formation of the immunoglobulins c) Ginsenosides stimulate the secretion of insulin.

d) It decreases serum cholesterol level.

e) None of the above.

6- Concerning glycyrrhizin, one of the following characters are true :

a) It is 50 times less sweet as sugar. b) It is glycosidal resin.

c) It is the potassium and calcium salt of glycyrrhetic acid.

d) It contains two molecules of glucuronic acid.

e) It acts as anti-inflammatory.

7- One of the following drugs can be used to stop bleeding:

a) Senega root. b) Jalap root. c) Sarsaparilla root.

d) Krameria root e) Calumba root.

8- 66% sulphuric acid test is used for identification of:

a) Gentian powder. b) Sweet wood powder.

c) Aconite powder. d) Jalap powder. e) Rauwolfia powder.

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9- Ipomea purga can be differentiated from Orizaba Jalap by all of the following except

a) Comparing between sizes.

b) The percentage of soluble resin in ether.

c) Shape of the starch granules.

d) Fluoresces under Ultra-violet light.

e) The purgative effect.

10- Enzymatic hydrolysis of gentiopicrin gives:

a) Gentiogenin and one dextrose b) Gentiogenin and two dextrose c) Gentiogenin and trisaccharide gentianose

d) Trisaccharide gentianose e) Disaccharides gentiobiose

Question II - Complete the blank spaces:

1- Liquorice has asprin-like action due to ………...

2- Two types of saponins in gensing are ……….……… and

………..….

3- Sarsaparilla root can be used in ……… due to the presence of ………. as active constituents

4- Convolvulin is an example of ……….…… class of active constituents while ……….…….. is an example of bitter glycosides

Question III Give reason(s) for each of the following:

1- Sarsaparilla root can be used in synthesis of cortisone and other steroids.

………

………

………

2- Ginseng is contra-indicator in liver transplantation.

………

………...……….

………

3- Liquorice is not prescribed for hypertensive patients.

………

………

………

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