ANGIOTENSIN-II
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Administration of angiotensin II and a bradykinin B2 receptor blocker in midpregnancy impairs gestational outcome in guinea pigs
... This study leaves unresolved questions regarding why additive effects of combined interventions were observed for some, but not all, study parameters. The discordance between the lack of additive effect on fetal weight ...
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Fibrotic response induced by angiotensin II requires NAD(P)H oxidase induced reactive oxygen species (ROS) in skeletal muscle cells
... Our results indicate that Ang-II induced a significant increase in intracellular calcium levels which was not inhibited by NAD(P)H oxidase blockers, suggesting that Ang-II-induced ROS are not in- volved in ...
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Angiotensin II increases fibronectin and collagen I through the beta catenin dependent signaling in mouse collecting duct cells
... MC. Angiotensin II increases fibronectin and collagen I through the  -catenin-dependent signaling in mouse collecting duct ...of angiotensin II (ANG II) to renal and tubular fibrosis ...
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Angiotensin II receptor type 1 blockade decreases CTGF/CCN2 mediated damage and fibrosis in normal and dystrophic skeletal muscles
... Connective tissue growth factor (CTGF/CCN-2) is mainly involved in the induction of extracellular matrix (ECM) proteins. The levels of CTGF correlate with the degree and severity of fibrosis in many tissues, including ...
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Angiotensin II Induced Mesangial Cell Damage Is Preceded by Cell Membrane Permeabilization Due to Upregulation of Non Selective Channels
... with angiotensin II (AngII) developed oxidative stress (OS, thiobarbituric acid reactive species (TBARS) and generated pro-inflammatory cytokines (ELISA; IL-1 β and TNF- α ...
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Angiotensin II Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy
... of angiotensin II (Ang II). Ang II can regulate proliferation, migration, ROS production and hypertrophy of vascular smooth muscle cells ...Ang II can affect VSMCs remain to be fully ...
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Rac2 GTPase activation by angiotensin II is modulated by Ca2C/calcineurin and mitogen-activated protein kinases in human neutrophils
... 4 Angiotensin II enhances Rac2 GTP-binding activity in an AT1 receptor-dependent manner in human ...Ang II for 10 min or with 10 nM fMLP for 3 min at 37 8C, where ...
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The angiotensin (1 7)/Mas axis reduces myonuclear apoptosis during recovery from angiotensin II induced skeletal muscle atrophy in mice
... circulating angiotensin II (Ang II) levels [42, 53]. Ang II is the main peptide of the classical axis of the renin-angiotensin system ...Ang II has been demonstrated to induce ...
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Angiotensin II Independent Upregulation of Cyclooxygenase 2 by Activation of the (Pro) Renin Receptor in Rat Renal Inner Medullary Cells
... the pressor and antinatriuretic effects of angiotensin II (AngII) in the renal medulla. The (pro)renin receptor (PRR) is abundantly expressed in the collecting ducts (CD) and its expression is augmented by ...
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Angiotensin (1 7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor dependent mechanism
... MuRF-1. Angiotensin II (AngII) induces muscle atrophy. Angiotensin-(1–7) [Ang-(1–7)], through its receptor Mas, produces the opposite effects than ...
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Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD and p38 MAPK dependent mechanism in skeletal muscle
... skeletal muscle. We demonstrated that AT-2 protein lev- els are increased by TGF-b in a dose-dependent manner. However, AT-1 levels remain unchanged. In vivo experiments showed that injection of TGF-b1 in skeletal mus- ...
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Angiotensin II induced pro fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells
... The myoblasts were serum-starved for 18 h and then incubated for different times with Ang-II (500 nM). The total RNA was isolated from the cell cultures at the times indicated in the figures using Trizol ...
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Anticuerpos contra el receptor 1 de angiotensina II pretrasplante: un factor de riesgo para la disminucin de la funcin del injerto en el periodo postrasplante temprano?
... month post-transplant, as reflected by a decreased eGFR in the AT 1 Rab group when compared with the HLA-DSA positive group and that with no antibod- ies (62.9 mL/min vs. 81.9 mL/min vs. 78.5 mL/min, respectively). ...
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Analytical strategies for the characterization, identification, and quantification of peptides and proteins of interest in the prevention and understanding of hypertension
... Renin- angiotensin system plays a crucial role in the regulation of blood pressure in human ...organism. Angiotensin I converting enzyme (ACE) converts angiotensin I into angiotensin ...
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Renin angiotensin system may trigger kidney damage in NOD mice
... decapeptide Angiotensin-I (AI), thus releasing the vasopressive octapeptide angiotensin-II and the dipeptide ...histidyl-leucine. Angiotensin-II plays an important role in the ...
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Utero placental expression of angiotensin (1 7) and ACE2 in the pregnant guinea pig
... to angiotensin II recep- tor 1 (AT1-AA) participate in the physiopathology of preeclampsia, stressing the prominence of the renin- angiotensin system (RAS) in this condition ...
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Papel de la angiotensina II en pacientes con diabetes mellitus, dislipidemias e infección previa por arbovirus
... of angiotensin II has recently been described in viral infections, however, the role that angiotensin II could play in the immunopathogenesis of arbovirus infection such as Dengue, Zika and ...
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Inhibition of the angiotensin converting enzyme decreases skeletal muscle fibrosis in dystrophic mice by a diminution in the expression and activity of connective tissue growth factor (CTGF/CCN 2)
... and angiotensin II (Ang-II; Abraham 2008; Pereira et ...renin angiotensin system (RAS), together with angiotensin II receptor type I (AT-1 receptor) and the ...
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Efecto gastroprotector de Lagenocarpus rigidus (Kunth) Ness (tirica do Nativo) extracto de hoja contra las lesiones gstricas inducidas por indometacina
... of angiotensin converting enzyme (I-ACE) seems to have gastroprotective effect by enhancing level of endogenous ...reduces angiotensin II formation and activates renin-kallicrein-kinin system ...
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Pioglitazone upregulates hepatic angiotensin converting enzyme 2 expression in rats with steatohepatitis
... Objective. Angiotensin II, one component of renin-angiotensin system (RAS), is formed from Ang I by the catalysing of angiotensin converting enzyme ...(ACE). Angiotensin II plays ...
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