Bile acid
The nuclear receptor FXR, but not LXR, up regulates bile acid transporter expression in non alcoholic fatty liver disease
... Figure 1. Gene expression of nuclear receptors and bile acid transporters SS and NASH liver biopsies. FXR, SHP, NTCP, and BSEP gene expression was significantly upregulated in NASH vs. simple steatosis (SS) ...
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Intrahepatic cholestasis of pregnancy: Changes in maternal fetal bile acid balance and improvement by ursodeoxycholic acid
... total bile acid levels (above 11,0 µµµµµmol/L), en- hanced cholic acid percentage (above 42%) and de- creased glycine/taurine bile acid ratio (below ...of bile acids from mother ...
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Effects of bile acid sequestration on hepatic steatosis in obese mice
... Background. Bile acid sequestration (BAS) with resins has shown antidiabetic effects in both humans and ...to bile secretion, lipid and glucose metabolism were ...biliary bile acid ...
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The Role of the Gut Microbiota in Bile Acid Metabolism
... between bile acid synthesis and gut ...between bile acids and the gut microbio- ta is close and complementary. Bile acids control gut bacteria overgrowth and protect against in- flammation ...
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Effect of cholecystectomy on bile acid synthesis and circulating levels of fibroblast growth factor 19
... governing bile acid (BA) synthesis and gallbladder (GB) ...in bile and serum by ELISA. Basal and BA (chenodexycholic acid, CDCA) induced FGF19 expression and secretion was analyzed in primary ...
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Fecal bile acid excretion and messenger RNA expression levels of ileal transporters in high risk gallstone patients
... dependent bile acid transporter (Astb); Fabp6, which is the gene for ileal lipid binding protein (ILBP); Abcc3, which is the gene for multidrug resistance-associated protein 3 (MRP3); or Ost and Ost , which ...
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Bile Acid Physiology
... primary bile acids (BAs) are synthetized from cholesterol in the liver, conjugated to glycine or taurine to increase their solubility, secreted into bile, concentrated in the gallbladder during fasting, and ...
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Bile acids content in brain of common duct ligated rats
... failure. Bile duct ligated rats constitute an interesting model to study the mechanism of cholestasis, and its action on seve- ral organs and tissues, including the ...brain bile acids individually in ...
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Effect of cholecystectomy on hepatic fat accumulation and insulin resistance in non obese Hispanic patients : a pilot study
... BA: Bile acid; BMI: Body mass index; FF: Fat fraction; FGF19: Fibroblast growth factor 19; GSD: Gallstone disease; HDL: High density lipoprotein; HFC: Hepatic fat content; HOMA-IR: Homeostasis model ...
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Bile Acids in Cholestasis and its Treatment
... canalicular bile and contribute to regulate biliary pH, which is important for activation of pancreatic enzymes and the absorption of li- pophilic organic ...sodium-dependent bile acid transporter ...
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Biliary secretion and excretion in health and disease: Current concepts
... a bile acid to taurine or glycine (or a bile al- cohol to ...conjugated bile salts are impermeable to cell membranes and have a re- markable ability to dissolve biliary phosphatidylcho- line, ...
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La lista de sus publicaciones se puede descargar en este enlace
... Wieland, H. and H. Sorge (1916). "Examination of the gallic acid. III. Report. The structural relationship between carbonic acid and desoxy-carbonic acid." Hoppe-Seylers Zeitschrift Fur ...
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Transcriptional regulation of hepatobiliary transport systems in health and disease: Implications for a rationale approach to the treatment of intrahepatic cholestasis
... novalent bile acids are excreted into the bile canaliculus via BSEP – deter- mining bile salt dependent bile flow-, while divalent bile acids and anionic conjugates ...determining ...
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Clinical analysis of laparoscopic cholecystectomy for elderly patients with acute cholecystitis
... restore bile flow, it generally develops to the symptoms like suppurative inflammation, cyst wall necrosis, and perforation, so for patients with acute cholecystitis within 72 h of onset, there has a consensus ...
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Chemical priming of immunity without costs to plant growth
... (R)-b-glutamic acid and RBH to IBI1 with different molecular orientations than ...amino acid ligands, our subsequent experiments provide multiple lines of evidence that the resistance response to RBH ...
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Endoscopy Ultra- Sonography –Guided Biliary Drainage in the Surgical –Endoscopy Era
... As stated above, puncture of the CBD from the duodenum (EUS-CDS) is the most common approach. A similar appro- ach from the stomach (EUS-choledocho gastrostomy or EUS-choledocho antrostomy) may also be used in selected ...
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La conferencia de aceptación del Premio Nobel se puede leer aquí
... an acid very similar in composition to desoxycholic acid which he called "choleic ...an acid which is isomeric with desoxycholic acid, until in 1916 it could be shown that it consists of a ...
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An unusual type of biliar cyst: A case report
... mon bile duct and a large cystic mass of unclear origin in the liver, there was no certainty that the cyst continue to the intrahepatic bile tract (Figure ...
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Development and validation of a genome scale metabolic model for the malolactic bacterium oenococcus oeni
... Only one continuous culture could be found for O. oeni (Zhang & Lovitt, 2006). In this study, the growth performance of the strain NCIMB 11648 was assessed at dilution rates between 0.007 and 0.052 . The authors ...
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Diagnostic and therapeutic cholangioscopy in biliary diseases: a prospective study in Peru
... Cholangioscopy was used for the diagnosis of indeterminate bile duct strictures in 13 patients (Tables 3 and 4). The location of the lesion was seen in distal, middle, proximal, intrahepatic bile duct at 4, ...
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