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Cell activation

The antioxidant effect of β-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation.

The antioxidant effect of β-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation.

... stellate cell (HSC) ...HSC activation with overproduction of extracellular matrix ...increased cell viability and significantly reduced the expression of fibrotic marker ...

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Functional Gap Junctions Accumulate at the Immunological Synapse and Contribute to T Cell Activation

Functional Gap Junctions Accumulate at the Immunological Synapse and Contribute to T Cell Activation

... T cell proliferation (42). Moreover, a role for GJs in T cell activation was recently de- scribed, and inhibition of GJIC was responsible for reduced IL-2 secretion and cell proliferation ...

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Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity

Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity

... T cell priming. This crosstalk contributed to T cell activation, intracellular Ca 2+ responses, and cytokine ...NK cell activation by DCs and NK cell–mediated cytotoxicity ...

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Desialylation of T lymphocytes overcomes the monocyte dependency of pokeweed mitogen induced T cell activation

Desialylation of T lymphocytes overcomes the monocyte dependency of pokeweed mitogen induced T cell activation

... and biotin-labelled PNA with mock-treated or Nase-treated (a) puri- Figure 6. (a) Capacity of PWM ( 10 mg/ml ), PNA (20 mg/ml ) and fied leukaemic CD5 + B cells and ( b) purified tonsil B cells banding PHA ( 0·3%, v/v) ...

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MicroRNA 146b regulates hepatic stellate cell activation via targeting of KLF4

MicroRNA 146b regulates hepatic stellate cell activation via targeting of KLF4

... Cell proliferation was analyzed using a Cell Counting Kit-8 (CCK-8, Beyotime, Shanghai, China), according to the manufacturers protocol. Briefly, cells were plated onto 96-well plates at a density of 5 x ...

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Coagulation factor Xa promotes metastasis through endothelial cell activation

Coagulation factor Xa promotes metastasis through endothelial cell activation

... use in combination with chemotherapy increased survival rates among lung small-cell carcinoma patients (compared to patients that only received chemotherapy) (Altinbas et al, 2004). Significantly, a twelve-month ...

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Rol del proteosoma 26S en la formación y función de la sinapsis inmune de los linfocitos B

Rol del proteosoma 26S en la formación y función de la sinapsis inmune de los linfocitos B

... Figure 7: The capacity of B cells to extract and present extracellular antigens relies on proteasome activity. (A) Antigen presentation assay for control and MG-132 pre-treated cells. ELISA quantified levels of IL-2 ...

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Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity

Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity

... the activation process, there are strong counter-regulating mechanisms for T cell activation, which are provided by inhibitory signaling ...T cell activation is ...T cell ...

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Human metapneumovirus keeps dendritic cells from priming antigen specific naive T cells

Human metapneumovirus keeps dendritic cells from priming antigen specific naive T cells

... T-cell activation when stimulated with hMPV- inoculated monocyte-derived DCs pulsed with a super- antigen 9 ...T-cell activation, 24,45 here we used an antigenic peptide that is presented to T ...

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Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

... T cell activation following CD3 ␨ subunit of the TCR complex and was found to be TCR ...PKC activation, resulted in impairment of F-actin translocation, suggesting that autophosphorylation of ...

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Observaciones sobre el congreso La patognesis del VIH, virus contra hospedero, Alberta, Canad, marzo 9 14, 2014

Observaciones sobre el congreso La patognesis del VIH, virus contra hospedero, Alberta, Canad, marzo 9 14, 2014

... This last strategy has rise considerable enthusi- asm, with histone diacetilase inhibitors (HDACis) as the most advanced intervention as HIV-1 antilatency agents in the clinical testing. Results of a pilot single- dose ...

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Respiratory syncytial virus infection and immunity

Respiratory syncytial virus infection and immunity

... T-cell activation levels that are sufficient to mediate viral clearance from the lungs, which promotes low levels of inflammation and hence reduced tissue ...T cell ratios prevailing in the blood of ...

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3BP2 Deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation

3BP2 Deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation

... 3BP2-deficient mice were viable and exhibited no apparent anatomical defects. Hemizygous point mutations of 3BP2 in humans have been associated with cherubism, which is char- acterized by multiple symmetric cysts in the ...

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Development of a cell formation system

Development of a cell formation system

... scribed by a decaying oscillation [22]. The operation in discontinuous conduction mode can there- fore also influence the stability of the control system. This problem can be solved in three ways: Parametrization of the ...

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LaST: Language Study Tool

LaST: Language Study Tool

... second activation record (cells 10 to 13) and the variable root, allocated there, points to the node with value ...the activation record of the second recursive call is created (cells 14 to 17) with the ...

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Minireview: Deciphering direct and indirect influence of thyroid hormone with mouse genetics

Minireview: Deciphering direct and indirect influence of thyroid hormone with mouse genetics

... granule cell migration, in- creased cell death, and stunted Purkinje cell arborization are all neurodevelopmental defects associated with con- genital ...

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Notch signal protects non parenchymal cells from ischemia/ reperfusion injury in vitro by repressing ROS

Notch signal protects non parenchymal cells from ischemia/ reperfusion injury in vitro by repressing ROS

... Figure 1. A. Notch signal deficiency led to increased ROS accumulation and aggravated cell death in HUVECs subjected to I/R injury. Total cellular proteins were extracted from I/R-injured HUVECs, electrophoresed ...

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Alteraciones en la metilación del promotor del gen mgmt como factor predictivo en pacientes con diagnóstico de astrocitoma

Alteraciones en la metilación del promotor del gen mgmt como factor predictivo en pacientes con diagnóstico de astrocitoma

... cancer cell proliferation and ...PR activation by PKC induces the migration and invasion of glioblastoma derived cell lines and if PKCα and δ isoforms are involved in PR ...PKC activation with ...

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Angiotensin II Induced Mesangial Cell Damage Is Preceded by Cell Membrane Permeabilization Due to Upregulation of Non Selective Channels

Angiotensin II Induced Mesangial Cell Damage Is Preceded by Cell Membrane Permeabilization Due to Upregulation of Non Selective Channels

... Around two dozens of human and rodent Cx isoforms have been identified to date [13]. Each Cx is named according to their predicted molecular weight, preceded by the suffix Cx [14]. In cortical astrocytes, IL-1 β and TNF- ...

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p75 Neurotrophin Receptor mediated Apoptosis in Sympathetic Neurons Involves a Biphasic Activation of JNK and Up regulation of Tumor Necrosis Factor alpha converting Enzyme/ADAM17

p75 Neurotrophin Receptor mediated Apoptosis in Sympathetic Neurons Involves a Biphasic Activation of JNK and Up regulation of Tumor Necrosis Factor alpha converting Enzyme/ADAM17

... As discussed above, JNK activation promotes cell death through multiple mechanisms. Moreover, our results suggest that, even in regulating p75NTR cleavage, there is more than one function required of this ...

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