Dendrimers and dendrons

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Mesoporous Silica Nanoparticles Decorated with Carbosilane Dendrons as New Non viral Oligonucleotide Delivery Carriers

Mesoporous Silica Nanoparticles Decorated with Carbosilane Dendrons as New Non viral Oligonucleotide Delivery Carriers

... achieved and beyond this limit the inorganic support surface is essentially blocked and therefore, even though anchoring points are available, there is no space for more dendrimers to reach them [ 39 ...

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Synthesis and electrochemical characterization of donor-acceptor phenylazomethine dendrimers

Synthesis and electrochemical characterization of donor-acceptor phenylazomethine dendrimers

... the core for the attachment of electron donor conjugated dendrons in the convergent syntheses of dendrimers 4 and 5. Thus, generation of p-nitrobenzilimidate by heating p- nitrobenzonitrile (10) in ...

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Synthesis of degradable cationic carbosilane dendrimers based on Si O or ester bonds

Synthesis of degradable cationic carbosilane dendrimers based on Si O or ester bonds

... carbosilane dendrimers, we have designed new cationic systems through two different strategies: with inner Si-O bonds or with peripheral ester ...of dendrimers has been prepared by coupling carbosilane ...

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Dendronized Anionic Gold Nanoparticles: Synthesis, Characterization and Antiviral Activity

Dendronized Anionic Gold Nanoparticles: Synthesis, Characterization and Antiviral Activity

... size and structure, monodisperse and with a multivalent molecular ...applications and anionic dendrimers are being explored as anti-HIV ...molecules and we have developed anionic ...

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Amphiphilic Cationic Carbosilane PEG Dendrimers: Synthesis and Applications in Gene Therapy

Amphiphilic Cationic Carbosilane PEG Dendrimers: Synthesis and Applications in Gene Therapy

... design and synthesis of Janus-type amphiphilic dendrimers composed of two types of dendrons, one based on the carbosilane moiety and the other on a PEG scaffold, both decorated with ammonium ...

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Controlled drug delivery strategies: Advances on the synthesis and molecular dynamics of dendrimers, and optimization of liposomes preparation by Dual Asymmetric Centrifugation

Controlled drug delivery strategies: Advances on the synthesis and molecular dynamics of dendrimers, and optimization of liposomes preparation by Dual Asymmetric Centrifugation

... Serna-­‐Saldívar and Nutriomics group for their financial support by PBI (Programa de Becarios de Investigación, Tecnológico de Monterrey) ...of dendrons and dendrimers we would like to ...

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Agency as Irony: Akrasia and (In)Action in Antony and Cleopatra and Othello

Agency as Irony: Akrasia and (In)Action in Antony and Cleopatra and Othello

... volition and action, intention and achievement, has traditionally been at the core of western understandings of the major dramatic sub- genres ...comic and tragic plots and have long claimed a ...

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Synthesis of chiral carbosilane dendrimers with L cysteine and N acetyl L cysteine on their surface and their application as chiral selectors for enantiomer separation by capillary electrophoresis

Synthesis of chiral carbosilane dendrimers with L cysteine and N acetyl L cysteine on their surface and their application as chiral selectors for enantiomer separation by capillary electrophoresis

... water and 40 min with the buffer in basic conditions and with MeOH for 5 min, NaOH 1 M for 25 min, 5 in with Milli-Q water, 5 min with HCl ...M and 30 min with the buffer in acid ...buffer and ...

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There are genus one curves of every index over every infinite, finitely generated field

There are genus one curves of every index over every infinite, finitely generated field

... v, and pull back via the isomorphism to get a class η in H 1 (K, ...n, and since it is locally trivial except at v, by Lemma 27 it also has index ...v and η v ∈ H 1 (K v , E) of order ...

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Effect of anti-inflammatory dendrimers on the pathogenesis of multiple sclerosis

Effect of anti-inflammatory dendrimers on the pathogenesis of multiple sclerosis

... Drugs and chemical compounds in general, can induce different cytotoxicity mechanisms including destruction of cell membranes, protein synthesis arrest, irreversible binding to receptors, ...assay and the ...

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Polyanionic carbosilane dendrimers as a new adjuvant in combination with latency reversal agents for HIV treatment

Polyanionic carbosilane dendrimers as a new adjuvant in combination with latency reversal agents for HIV treatment

... reactivation and transcription ...“shock and kill” method with dendrimers, which not only inhibit the entry of new replicative viruses, but also help with the reactivation activity of ...our ...

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In Vitro anticancer properties of copper metallodendrimers

In Vitro anticancer properties of copper metallodendrimers

... nanotubes, and dendrimers [17,18]. Dendrimers were synthesized for the first time in the 1970s and now are quite popular in the field of drug delivery ...structure and a high degree of ...

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Allergic reactions to β-lactam antibiotics: chemical approaches for improving in vitro diagnosis

Allergic reactions to β-lactam antibiotics: chemical approaches for improving in vitro diagnosis

... 190 and Lys 212 appear in 8/8 patients along with other residues that vary from one individual to another [101], and in the case of AX, piperacillin and CLV, Lys 190 is a common modified residue in ...

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Self Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction

Self Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction

... ADs and alkyl-tail ...G2-15C and G2-13C systems, can be explained by a single counterion that was trapped in the micelle-siRNA ...water and specially, counterions also appear delineating the shape of ...

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Nanomaterials and Nanosystems for Biomedical Applications – M. Reza Mozafari

Nanomaterials and Nanosystems for Biomedical Applications – M. Reza Mozafari

... consistency, and are classified into two groups: monostarch phosphates and distarch phosphates (cross-linked ...paste and gel properties of the ...pyro-, and tripolyphosphoric acids and ...

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Strategies for penicillin V dendronization with cationic carbosilane dendrons and study of antibacterial properties

Strategies for penicillin V dendronization with cationic carbosilane dendrons and study of antibacterial properties

... antibiotics and a polymer containing cationic cobaltocenium units exhibit synergistic effects against methicillin resistant ...-lactamase and effectively lysing bacterial ...

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Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake

Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake

... shorter and more flexible molecules such as ...neutral dendrimers as a scaffold to introduce other functional groups has been ...of dendrimers using molecular dynamics simulations, in order to ...

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Carbosilane cationic dendrimers synthesized by thiol ene chemistry and their use as antibacterial agents

Carbosilane cationic dendrimers synthesized by thiol ene chemistry and their use as antibacterial agents

... The stability study of compound 19 against pH, time and temperature showed that the activity of this compound is kept in all the measured conditions as is shown in Figure 7 (near 100 % growth inhibition). However, ...

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Function Oriented Molecular Design: Dendrimers as novel antimicrobials

Function Oriented Molecular Design: Dendrimers as novel antimicrobials

... toxicity and the significant improvement of the inhibitory activity against the parasites in both in vitro and in vivo studies ...worldwide and constitutes a serious public health problem especially ...

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Self Assembly behavior of amphiphilic janus dendrimers in water: a combined experimental and coarse grained molecular dynamics simulation approach

Self Assembly behavior of amphiphilic janus dendrimers in water: a combined experimental and coarse grained molecular dynamics simulation approach

... Janus dendrimers (JDs) are repetitively branched molecules with hydrophilic and hydrophobic components that self-assemble in water to form a variety of morphologies, including vesicles analogous to ...

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