Dendritic cells
Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases
... Dendritic cells (DCs) play a key role in the activation of the immune response against pathogens, as well as in the modulation of peripheral tolerance to self-antigens ...T cells and limiting B cell ...
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Virulent Salmonella Enterica Serovar Typhimurium Evades Adaptive Immunity by Preventing Dendritic Cells From Activating T Cells
... Dendritic cells (DCs) constitute the link between innate and adaptive immunity by directly recognizing pathogen-associated molecular patterns (PAMPs) in bacteria and by presenting bacterial antigens to T ...
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Tolerogenic dendritic cells as a therapy for treating lupus
... (TLRs), dendritic cells (DCs), and type I interferons (IFNs), in SLE ...T cells by modifying cytokine profiles, thereby ameliorating immune ...immune cells are currently being ...
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Immune complex induced enhancement of bacterial antigen presentation requires Fc gamma Receptor III expression on dendritic cells
... that dendritic cells (DCs) residing at the infection site recognize pathogen-associated molecular patterns (PAMPs) ...T cells (1, ...T cells (7), interfering with their function can be highly ...
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Human metapneumovirus keeps dendritic cells from priming antigen specific naive T cells
... conventional dendritic cells ...T cells (OT-II), which not only display reduced pro- liferation, but also show a marked reduction in surface activation markers and interleukin-2 ...T cells, ...
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Caveolin 1 expression increases upon maturation in dendritic cells and promotes their migration to lymph nodes thereby favoring the induction of CD8+ T cell responses
... Dendritic cells (DCs) are professional antigen-presenting cells specialized in initiating adaptive T cell responses. DCs circulate and patrol peripheral tissues, taking up protein antigens and ...
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Carbon monoxide decreases endosome lysosome fusion and inhibits soluble antigen presentation by dendritic cells to T cells
... of dendritic cells (DCs) and protects in vivo and in vitro antigen- specific ...T cells by blocking antigen trafficking at the level of late endosome– lysosome ...
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Apoptosis-based immunotheraphy for thype 1 diabetes: from dendritic cells to antigen-specific liposomes
... harvesting, cells were immediately lysed in 350µl lysis buffer (RLT) to prevent unwanted changes in the gene expression profile, vortex and frozen at -70ºC until ...
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Generation of Tolerogenic Dendritic Cells for Cell Therapy in Multiple Sclerosis
... immune cells that cause damage (T EFF cells) and cells with suppressive capabilities (T REG cells and tolerogenic ...T cells to produce IFN-γ (T H 1 cells), IL-4 (T H 2 ...
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Synergistic Effect between Amoxicillin and TLR Ligands on Dendritic Cells from Amoxicillin-Delayed Allergic Patients.
... The cytokine production in the supernatants from LTT after stimulation with AX and TLR ligands alone and in combination in DTH and controls was also evaluated. Comparisons with the Wilcoxon test for related samples in ...
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Cyclosporin A treated Dendritic Cells may affect the outcome of organ transplantation by decreasing CD4+CD25+ regulatory T cell proliferation
... DC activation: CDllc + DC purified on day 5, were re-plated at 1 x 10 6 cells/ml in 250 ml of RPMI 1640 supplemented with 10% FBS and rGM-CSF ± CsA (750 ng/ mL) and activated with 100 ng/ml LPS (Sigma, St. Louis, ...
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Impaired B cells survival upon production of inflammatory cytokines by HIV-1 exposed follicular dendritic cells.
... B cells suggest that exposure of FDCs to HIV‑1 in vivo can contribute to inflammation within germinal centers and that this pathological event may impair B cell survival and contribute to impaired B cell responses ...
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The herpes simplex virus type 2 glycoprotein D and host IRE 1α/XBP 1 pathway modulate the functions of dendritic cells after infection with this virus
... epithelial cells early after infection, particularly that mediated by IRE-1α to avoid ER stress elicited by the massive production of viral proteins required for virion assembly (Burnett et ...epithelial ...
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Dissecting thyroid hormone transport and metabolism in dendritic cells
... Immature bone marrow DCs (iDCs) were obtained as described (Mascanfroni et al. 2008). Briefly, bone marrow progenitors were collected from the femurs of 6- to 10-week-old female C57BL/6 mice and cultured in RPMI-1640 10% ...
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New aspects in celiac disease
... tolerogenic dendritic cells with the induction of anergic and immunosuppressive T cells, and an arrest of maturation/ activation of dendritic ...on dendritic cells is tightly ...
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Aldosterone as a modulator of immunity: implications in the organ damage
... immune cells. Moreover, mineralocorticoid receptor expression by immune cells, such as dendritic cells, has opened a new window of possibilities of interaction between the endocrine and immune ...
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Mesenchymal stem cell therapy in retinal and optic nerve diseases: An update of clinical trials
... their diverse potentialities to differentiate into specific functional cell types to regenerate damaged optic nerves, supporting tissues and vasculature. They will use clinical grade purification system (CliniMACS) and ...
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Structure activity relationship study of cationic carbosilane dendritic systems as antibacterial agents
... (34S) was tested against antibiotic resistant bacteria. For these experiments a penicillin-resistant S. aureus strain and the induced resistant E. coli strain generated in the previous resistance assays were used. Whilst ...
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A RhoA Signaling Pathway Regulates Dendritic Golgi Outpost Formation
... of the cis-Golgi), or galactosyl-transferase 2 (GalT2, a resident transferase preferentially associated with the trans-Golgi), or b-1, 4-N-acetylgalactosaminyltransferase (GalNAcT, a resident transferase associated with ...
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PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B NMDA receptors
... We demonstrate that, concurrent with strong overall and synaptic expression of the NR2B subunit, large scale structural changes occur in the dendrites of developing hippocampal cultures, with branch number peaking at 7 ...
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