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Dendritic spines

Random positioning of dendritic spines in the human cerebral cortex

Random positioning of dendritic spines in the human cerebral cortex

... Dendritic spines establish most excitatory synapses in the brain and are located in Purkinje cell's dendrites along helical paths, perhaps maximizing the probability to contact different ...500 ...

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Random positions of dendritic spines in human cerebral cortex

Random positions of dendritic spines in human cerebral cortex

... of dendritic spines in pyramidal neurons from Rhe- sus prefrontal cortex, reporting nonrandom clusters of spines in apical, albeit not oblique, dendrites (Yadav et ...apical/basal dendritic ...

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GSK-3β overexpression alters the dendritic spines of developmentally generated granule neurons in the mouse hippocampal dentate gyrus

GSK-3β overexpression alters the dendritic spines of developmentally generated granule neurons in the mouse hippocampal dentate gyrus

... of dendritic spines of developmentally generated granule ...of dendritic spines (namely, stubby, thin and ...thin spines, whereas the head diameter of mushroom spines was ...

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BDNF Regulates Rab11 Mediated Recycling Endosome Dynamics to Induce Dendritic Branching

BDNF Regulates Rab11 Mediated Recycling Endosome Dynamics to Induce Dendritic Branching

... for dendritic branching in Drosophila neurons (Yang et ...of dendritic spines and regulate local trafficking of AMPA receptors to the plasma membrane in hip- pocampal neurons (Kopec and Malinow, ...

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Volume Haptics and Dendritic Spine Editing

Volume Haptics and Dendritic Spine Editing

... This procedure takes place into a general segmentation workflow such as the one pre- sented in [Mei10] and shown in Fig. 4.1. This figure illustrates the key processing steps for neuronal segmentation. The di↵erent steps ...

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PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B NMDA receptors

PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B NMDA receptors

... normal dendritic architecture in maturing hippocampal ...tertiary dendritic branches strongly increases during the first 7 DIV and then gradually but profoundly drops over the next 2 weeks in culture ...

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The evolution of the brain, the human nature of cortical circuits and intellectual creativity

The evolution of the brain, the human nature of cortical circuits and intellectual creativity

... small dendritic shafts and dendritic spines on oblique dendrites of pyramidal cells within a very narrow column of cortical tissue (DeFelipe et ...

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Improved efficiency of ibuprofen by cationic carbosilane dendritic conjugates

Improved efficiency of ibuprofen by cationic carbosilane dendritic conjugates

... These dendritic systems contain hydrophobic, ibuprofen ligand and carbosilane framework, and hydrophilic, ammonium groups, moieties and therefore, the exposure of the hydrophobic parts in aqueous solution tend to ...

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IgG keeps virulent Salmonella from evading dendritic cell uptake

IgG keeps virulent Salmonella from evading dendritic cell uptake

... Dendritic cells (DCs) are phagocytic professional antigen-presenting cells that can prime naive T cells and initiate anti-bacterial immunity. How- ever, several pathogenic bacteria have developed virulence ...

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Targeting dendritic cell function during systemic autoimmunity to restore tolerance

Targeting dendritic cell function during systemic autoimmunity to restore tolerance

... that dendritic cells (DCs) play a crucial role at initiating the immune response against pathogens, this cell type also contributes to maintain peripheral immune tolerance ...

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Enhancing dendritic cell immunotherapy for melanoma using a simple mathematical model

Enhancing dendritic cell immunotherapy for melanoma using a simple mathematical model

... There is hope that one of these immunotherapies, the Sipuleucel-T treatment shows that the personalized treatment with antigen-presenting cells (APCs) could be effi- cient to extend the life of people suffering from ...

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Fluorescein labelled cationic carbosilane dendritic systems for biological studies

Fluorescein labelled cationic carbosilane dendritic systems for biological studies

... allowed us to obtain the corresponding fluoresceinated cationic derivatives. The toxicity of these dendritic molecules was studied by MTT and their interaction with siRNA Nef by electrophoresis. Finally, second ...

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Generation of Tolerogenic Dendritic Cells for Cell Therapy in Multiple Sclerosis

Generation of Tolerogenic Dendritic Cells for Cell Therapy in Multiple Sclerosis

... DC, dendritic cell; DCtol, tolerogenic dendritic cell; HLA-G, human leukocyte antigen G; MΦ, macrophage; Mc, microglial cell; ICOSL, inducible costimulatory molecule ligand; IFN-γ, interferon γ; IL-, ...

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Boletín mensual del Observatorio Magnético de la Base Orcadas del Sur : Marzo 2017

Boletín mensual del Observatorio Magnético de la Base Orcadas del Sur : Marzo 2017

... los spines protónicos, o núcleo del átomo de hidrógeno en el caso de un hidrocarburo o agua, para medir la intensidad total del campo magnético ...Los spines protónicos del agua, kerosén, alcohol, ...

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Protein kinase D regulates trafficking of dendritic membrane proteins in developing neurons

Protein kinase D regulates trafficking of dendritic membrane proteins in developing neurons

... In contrast, no such effects were ob- served in neurons. Thus, when Golgi mor- phology was analyzed with an antibody against GM130, a marker of the cis-Golgi, or after ectopic expression of GalT2-GFP, a marker of the ...

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Human metapneumovirus keeps dendritic cells from priming antigen specific naive T cells

Human metapneumovirus keeps dendritic cells from priming antigen specific naive T cells

... Figure 6. Neutralization of type I interferons (IFNs) does not restore T-cell activation, (a) IFN- a and (b) IFN- b secretion by dendritic cells (DCs) was measured by ELISA in supernatants collected 24 hr ...

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Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity

Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity

... treatments. Dendritic cells (DCs) have emerged as key players in developing and maintaining adaptive immunity due to their capacity to prime and modulate T cell ...

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Interacción Candida albicans-Hospedero: un proceso complejo en el que la inmunidad innata juega un importante papel

Interacción Candida albicans-Hospedero: un proceso complejo en el que la inmunidad innata juega un importante papel

... Candida albicans is a comensal microorganism that under certain circumstances is able to transform into a pathogen. This ability to switch constitute a virulence factor that C. albicans uses to invade and spread. The ...

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Tolerogenic dendritic cells as a therapy for treating lupus

Tolerogenic dendritic cells as a therapy for treating lupus

... Recently, promising new data has emerged revealing the crucial role of the innate immune system, including Toll-like receptors (TLRs), dendritic cells (DCs), and type I interferons (IFNs), in SLE pathogenesis. ...

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Effects of spine-shading on aspects of photosynthesis for three cactus species

Effects of spine-shading on aspects of photosynthesis for three cactus species

... Although spines can reflect some PPFD toward the stem surface of a cactus, spines typically decreases the incident PPFD on that surface, which can reduce photosynthetic activity if light quantity is lower ...

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