... damaged DNA has remained enigmatic until ...lowing DNAdamage, each ATM molecule phosphorylates the other on a serine residue at position 1981 within the FAT domain, a phosphorylation that releases ...
... cell damage can be estimated using various techniques ...assess DNAdamage in lymphocytes from children with ataxia-telangiectasia, and to measure chromosomal instability within the ...of DNA ...
... residual DNAdamage ...radiation-induced DNAdamage suggests that variation in cell radiosensitivity can be detected in vitro using radiosensitivity assays on PBLs from normal tissues of ...
... Villañoa et al., 2015). On the other hand, continuous practice with progressive intensities can induce adaptive responses by increasing the efficiency of endogenous antioxidant systems. In addition, it has been shown ...
... the damage inflicted directly by radiation, producing irreversible changes during DNA replica- tion or cell division or during the processing of DNAdamage by enzymatic repair processes ...
... of organic matter [1]. Exposure to these ubiquitous environmen- tal contaminants is a public health problem in cities with high industrial activity and heavy vehicular traffic, and also in some rural communities, due to ...
... oxidation-induced DNAdamage, and repair capacity in lymphocytes of NF1 patients compared to healthy control ...in DNAdamage were observed between controls and patients (p > ...but ...
... of DNAdamage, detectable within the first hours after exposure of the ...early DNA lesions caused by exposure to low doses of ionizing radiation in 41 workers from the departments of Radiology, ...
... oxidative DNAdamage. In addition, the DNAdamage observed in gill cells seems to be mainly influenced by exposure time and ...oxidative damage found in hemocytes exposed in vitro to ...
... that DNAdamage in the SEpC located on the luminal surface occurred due to the effects of the 2,6- ...though DNAdamage has occurred in the SEpC, taking into account that the life- time of ...
... Introduction. The progression of hepatic disease in chronic viral hepatitis is accompanied by an increased production of reactive oxygen species (ROS), as well as an accumulation of oxidative DNAdamage, ...
... in DNAdamage we observed in PC3-AR cells in response to ...induce DNAdamage via double strand breaks (DSBs) to mediate their transcriptional ...by DNA repair machinery such as poly ...
... mitochondrial damage can lead to direct or indirect oxida- tive DNAdamage and it has been found that a significant accumulation of the potentially mutagenic DNA lesion ei- ther at sub-toxic ...
... It has been indeed proposed that the associated accumulation of fumarate competitively inhibits the 2-oxoglutarate-dependent dioxygenases that regulate hypoxia-inducible factor (HIF), thus activating oncogenic hypoxia ...
... for DNA polymerase I during DNA replication in Escherichia ...rat DNA polymerase beta replace both the replicative and repair (BER) functions of DNA polymerase I in Escherichia coli (Sweasy ...
... Es muy común encontrar en los libros las definiciones de gen, muchas veces leerán, secuencia de DNA que codifica una proteína, eso es parcialmente falso. Porque hay genes que no codifican proteínas, algunos genes ...
... concerning damage caused by nuclear activities, as well as in the field of oil pollution at ...with damage caused by maritime transport of hazard- ous and noxious substances and also by transboundary ...
... 1998). DNA Checkerboard method offers the ability to include more potential periodontal pathogens in large-scale studies with a single analysis than is usually practicable with cultural ...
... de DNA foráneo en células de cultivo, el empleo de uno u otro método depende en gran medida de tipo celular que se emplee, del objetivo del estudio, el tamaño y naturaleza del gen a introducir, la economía del ...
... There are metabolic changes like weight, fluid and electrolyte loss. There could be certain endocrine disorders, such as sleep disturbances and disrup- ted circadian rhythm. Most astronauts experience problems with ...