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Drug delivery

Self Regulatory Drug Transport: An Intelligent Drug Delivery System

Self Regulatory Drug Transport: An Intelligent Drug Delivery System

... traditional drug delivery systems (DDSs) often as- sociated with many side effects, there as an always require- ment of approaches to develop new formulations for trans- porting medicine at required level ...

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Polyurethane Poly(2-(Diethyl Amino)Ethyl Methacrylate) blend for drug delivery applications

Polyurethane Poly(2-(Diethyl Amino)Ethyl Methacrylate) blend for drug delivery applications

... Equation 6 describes the drug delivery kinetics and it is only valid for the first 60% of the fractional release. For thin disks when n is equal to 0.5 the drug is said to diffuse with Fickian ...

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Drug delivery systems based on poly(e caprolactone) for cancer treatment

Drug delivery systems based on poly(e caprolactone) for cancer treatment

... of drug delivery systems have been ...enhance drug localization at the tumor region (by controlling its biodistribution profile) and, therefore, to increase the anti-tumor efficacy (even in ...

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Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery

Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery

... the drug delivery process revealed phenomena consistent with the interaction of liposomes with pRBCs immediately before or just after their constituent lipids are incorporated into the cell plasma membrane ...

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Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system

Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system

... self-microemulsifying drug delivery system (SMEDDS) was employed to improve the bioavailability of sulpiride, a drug which is poorly ...in-vitro drug release ...

1

Pulsatile drug delivery for the treatment of nocturnal asthma: a chronopharmaceutical approach

Pulsatile drug delivery for the treatment of nocturnal asthma: a chronopharmaceutical approach

... After evaluating the plug material and the capsule content separately, the complete pul- satile drug delivery system was investigated next. It consisted of formaldehyde treated cap- sule body containing ...

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Elastin like recombinamers as smart drug delivery systems

Elastin like recombinamers as smart drug delivery systems

... a drug was evaluated using two similar fluorophores, namely rhodamine B (red) and FITC (green), this latter possessing a negative charge, thus showing a charge-independent release of both molecules from the ...as ...

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Self Micro Emulsifying Drug Delivery Systems: A Strategy to Improve Oral Bioavailability

Self Micro Emulsifying Drug Delivery Systems: A Strategy to Improve Oral Bioavailability

... emulsifying drug delivery systems as well as its therapeutic ...Self-emulsifying drug delivery system (SMEDDS) has gained more attention due to enhanced oral bio-availability enabling ...

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Elastin like polypeptides in drug delivery

Elastin like polypeptides in drug delivery

... and drug delivery [126, ...in drug delivery and these have been extensively reviewed in the last few years [9, 128, ...for drug delivery has excellent potential but requires more ...

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Potential drug delivery system: study of the association of a model nitroimidazole drug with aggregates of amphiphilic polymers on aqueous solution

Potential drug delivery system: study of the association of a model nitroimidazole drug with aggregates of amphiphilic polymers on aqueous solution

... The results obtained in this study clearly show that the anhydride groups of the alternating vinylpyrrolidone- maleic anhydride copolymer reacts efficiently with ali- phatic amines to give a hemiamide. The conversion ...

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Development of gastro retentive drug delivery system of cephalexin by using factorial design

Development of gastro retentive drug delivery system of cephalexin by using factorial design

... method incorporating HPMC K4M, xanthan gum, guar gum, sodium bicarbonate and tartaric acid as gas generating agent. The influence of independent variables like, polymer: polymer ratio, polymer type and tartaric acid on ...

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Formulation and evaluation of osmotic drug delivery system of ibuprofen

Formulation and evaluation of osmotic drug delivery system of ibuprofen

... order delivery rate based on the principle of Osmosis, which is movement of a solvent from lower concentration of solute towards higher concentration of solute across a semi-permeable ...pumps drug ...

8

Gold Nanoparticles as Drug Delivery Agents. Detoxifying the Chemotherapeutic Drug Cisplatin

Gold Nanoparticles as Drug Delivery Agents. Detoxifying the Chemotherapeutic Drug Cisplatin

... We showed that the cisplatin-induced toxicity was clearly reduced using AuNPs-cisplatin. It is known that pharmacokinetic properties depend on physicochemical properties of the carrier rather than on the ones of the ...

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Development of squaramide based self immolative spacers for drug delivery

Development of squaramide based self immolative spacers for drug delivery

... Hence, methylation on the terminal amino group on our SIL should lead to an increase of the reaction rate in comparison with the non-methylated analogue (Scheme 5.3, R”). Conversely, squaramate ester 14b successfully ...

293

Development and Evaluation of Isoniazid Loaded Silk Fibroin Microsphere

Development and Evaluation of Isoniazid Loaded Silk Fibroin Microsphere

... For drug delivery, particularly protein drugs, silk materials exhibit controllable drug release kinetics and high encapsulation efficiency due to the crystalline beta-sheet ...

6

Functionalized nanostructures with application in regenerative medicine

Functionalized nanostructures with application in regenerative medicine

... as delivery system, could be the best choice for bone regeneration, as there is no need for long-term overexpression of bone morphogenetic proteins (BMP) to induce valid bone ...a delivery system to induce ...

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Nanomaterials and Nanosystems for Biomedical Applications – M. Reza Mozafari

Nanomaterials and Nanosystems for Biomedical Applications – M. Reza Mozafari

... the drug/dendrimer complexes were stable while the drugs were not released after storage at room temperature for about 10 ...mediated delivery of ODN-1 resulted in the down-regulation of in vitro VEGF ...

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Nanopartículas poliméricas de administración intranasal para la liberación de activos en el sistema nervioso central

Nanopartículas poliméricas de administración intranasal para la liberación de activos en el sistema nervioso central

... Results. Many of the drugs employed for the treatment of neurodegenerative diseases are not capable of going through the blood-brain-barrier (BBB) and reach the brain with enough concentration, being unable to apply ...

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