drug delivery system
Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system
... self-microemulsifying drug delivery system (SMEDDS) was employed to improve the bioavailability of sulpiride, a drug which is poorly ...in-vitro drug release ...
1
Hyaluronic acid-coated gold nanoparticles as an anticancer drug delivery system - Biological characterization and efficacy
... Our physico-chemical characterization strategy for the NM used in this study included various techniques established in the NCL cascade (http://ncl.cancer.gov/). When bare AuNPs were conjugated to HA, TEM showed no ...
199
Gastroretentive drug delivery system of captopril and hydrochlorothiazide bilayer tablet: formulation, optimization and in vivo evaluation
... gastroretentive drug delivery system (GRDDS) exhibiting a unique combination of floatation and bioadhe- sion to prolong residence in the stomach using captopril (CP) and hydrochlorothiazide (HCTZ) as ...
1
Self Regulatory Drug Transport: An Intelligent Drug Delivery System
... traditional drug delivery systems (DDSs) often as- sociated with many side effects, there as an always require- ment of approaches to develop new formulations for trans- porting medicine at required level ...
11
Development of gastro retentive drug delivery system of cephalexin by using factorial design
... The linear model for R3 (% drug release at 12 hr) found to be significant with F-value of 81.11 and P value 0.0022. In this case A, B are significant model terms with P value of 0.0235 and 0.0001 respectively. ...
16
A novel controlled drug delivery system for growth hormone applied to healing skin wounds in diabetic rats
... Abstract—Controlled release systems for drugs, hormones and growth factors can be particularly useful in tissue repair processes. These systems act as a biodegradable support containing the substance to be delivered, ...
16
Formulation and evaluation of a bilayer floating drug delivery system of nizatidine for nocturnal acid breakthrough
... the drug within 4 h. The drug release from HPMC K100M and HPMC K15M (F4-F9) was about ...of drug release (98%) was observed from the formulations based on HPMC K4M ...the drug release 4 ...
7
Formulation and evaluation of osmotic drug delivery system of ibuprofen
... order delivery rate based on the principle of Osmosis, which is movement of a solvent from lower concentration of solute towards higher concentration of solute across a semi-permeable ...osmotic system, ...
8
Elastin like recombinamers as smart drug delivery systems
... ELR-based drug carrier termed nanopeptifier, that was able to improve cellular uptake by controlled exposure of CPPs, which toggled in response to the application of external mild hyperthermia (Figure 3) ...
21
Drug delivery systems based on poly(e caprolactone) for cancer treatment
... better drug loading and release properties, and to a more suitable biodegradation profile 10 ...that drug-loaded micelles accumulated mostly in cytoplasm instead of cell nuclei, in contrast to free ...these ...
14
Development and Evaluation of Isoniazid Loaded Silk Fibroin Microsphere
... soaring drug dose has essential to be managed since merely little slice of the entire dose reaches the ...drugs delivery system which could be delivered using the respiratory route alongside with ...
6
Gold Nanoparticles as Drug Delivery Agents. Detoxifying the Chemotherapeutic Drug Cisplatin
... incubated 48 hours before performing the assay. Then EZ4U assay was performed as indicated by the manufacturer, but adding a previous washing step with PBS to remove the AuNPs in the media to avoid optical interferences ...
116
Elastin like polypeptides in drug delivery
... physiological conditions to form a local delivery depot [53]. The half-life of the resulting ELR-based coacervate at the administration site is at least 25-fold longer than for the soluble version [54]. Finally, ...
46
Nanomaterials and Nanosystems for Biomedical Applications – M. Reza Mozafari
... gene delivery systems and showed that dendritic poly (L-lysine) of the 6th generation (KG6) had high transfection efficiency into several cultivated cells with low ...gene delivery efficiency of ...
168
Nanopartículas poliméricas de administración intranasal para la liberación de activos en el sistema nervioso central
... nasal delivery come out. Thanks to the use of this system, many researches have shown an improvement in the clinical utility of the drug, reducing the dose and the frequency of dosing as well as the ...
9