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drug delivery systems

Drug delivery systems based on poly(e caprolactone) for cancer treatment

Drug delivery systems based on poly(e caprolactone) for cancer treatment

... of drug delivery systems have been ...enhance drug localization at the tumor region (by controlling its biodistribution profile) and, therefore, to increase the anti-tumor efficacy (even in ...

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Elastin like recombinamers as smart drug delivery systems

Elastin like recombinamers as smart drug delivery systems

... free drug, although different localizations were observed, with ELR- Dox being dispersed throughout the cytoplasm and free doxorubicin mostly internalized in the nucleus, suggesting different cell-death pathways ...

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Self Micro Emulsifying Drug Delivery Systems: A Strategy to Improve Oral Bioavailability

Self Micro Emulsifying Drug Delivery Systems: A Strategy to Improve Oral Bioavailability

... the drug to the lymphatic circulation of poor water soluble drugs depend on the type and con- centration of oil used in the ...the drug in contrast to the non-digestible lipids with which reduced bioavail- ...

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Self Regulatory Drug Transport: An Intelligent Drug Delivery System

Self Regulatory Drug Transport: An Intelligent Drug Delivery System

... traditional drug delivery systems (DDSs) often as- sociated with many side effects, there as an always require- ment of approaches to develop new formulations for trans- porting medicine at required ...

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Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system

Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system

... self-microemulsifying drug delivery system (SMEDDS) was employed to improve the bioavailability of sulpiride, a drug which is poorly ...in-vitro drug release ...

1

Formulation and evaluation of osmotic drug delivery system of ibuprofen

Formulation and evaluation of osmotic drug delivery system of ibuprofen

... The IR studies of pure Ibuprofen, Ibuprofen with higher proportion of sodium chloride (20%w/w), Ibuprofen with potassium chloride (20%w/w) and Ibuprofen with sodium chloride (20%w/w) and potassium chloride (20%w/w) were ...

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Pulsatile drug delivery for the treatment of nocturnal asthma: a chronopharmaceutical approach

Pulsatile drug delivery for the treatment of nocturnal asthma: a chronopharmaceutical approach

... pulsatile systems are gaining a lot of interest and attention, as they deliver the drug at the right site of action at right time and in right amount, thus providing spatial and tem- poral delivery ...

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Nanopartículas poliméricas de administración intranasal para la liberación de activos en el sistema nervioso central

Nanopartículas poliméricas de administración intranasal para la liberación de activos en el sistema nervioso central

... Results. Many of the drugs employed for the treatment of neurodegenerative diseases are not capable of going through the blood-brain-barrier (BBB) and reach the brain with enough concentration, being unable to apply ...

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Estimulacin cerebral profunda: Hacia la generacin de los dispositivos inteligentes

Estimulacin cerebral profunda: Hacia la generacin de los dispositivos inteligentes

... Deep brain stimulation (DBS) is a surgical procedure approved for the treatment of select patients with movement disorders, such as Parkinson’s disease, essential tremors, and dystonia. DBS uses electricity to ...

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Development and Evaluation of Isoniazid Loaded Silk Fibroin Microsphere

Development and Evaluation of Isoniazid Loaded Silk Fibroin Microsphere

... For drug delivery, particularly protein drugs, silk materials exhibit controllable drug release kinetics and high encapsulation efficiency due to the crystalline beta-sheet ...

6

Elastin like polypeptides in drug delivery

Elastin like polypeptides in drug delivery

... physiological conditions to form a local delivery depot [53]. The half-life of the resulting ELR-based coacervate at the administration site is at least 25-fold longer than for the soluble version [54]. Finally, ...

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Gold Nanoparticles as Drug Delivery Agents. Detoxifying the Chemotherapeutic Drug Cisplatin

Gold Nanoparticles as Drug Delivery Agents. Detoxifying the Chemotherapeutic Drug Cisplatin

... In this chapter, AuNPs-cisplatin were tested in in vitro assays to evaluate the cell and DNA accumulation as well as cell viability. More importantly, in vivo assays using tumor-bearing mice were also performed. This ...

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